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Kevin C. Halling, M.D., Ph.D.

  1. Medical Geneticist
  2. Pathologist
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Publications

  1. Whaley RD, Sill DR, Tekin B, McCarthy MR, Cheville JC, Ebare K, Stanton ML, Reynolds JP, Raghunathan A, Herrera Hernandez LP, Jimenez RE, Sharma V, Boorjian SA, Leibovich BC, Hofich CD, Alvand S, Pujari GP, Kipp BR, Ketterling RP, Geiersbach KB, Greipp PT, Sukov WR, Halling KC, Gupta S. Evaluation of 3,606 renal cell tumors for TFE3 rearrangements and TFEB alterations via fluorescence in situ hybridization, next generation sequencing, and GPNMB immunohistochemistry. Hum Pathol. 2025 May 15; 105797 [Epub ahead of print]
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  2. Gonzalez-Bosquet J, Shahi M, Yadav S, Kanwar N, Alvand S, Sosa C, Dowdy SC, Halling KC, Weroha SJ, Bakkum-Gamez JN, Podratz KC. ECPPF stratification identifies occult high-risk subgroups in stage I, grade 1 or 2, View PubMed
  3. Gupta S, Dasari S, Warren RR, Shen W, Urban RM, Stanton ML, Lohse CM, Holdren MA, Hoenig MF, Pitel BA, Smoley SA, Nelson SW, Torell NR, Moon AC, Nelson LM, Garcia JJ, Lucas PC, Halling KC, Kipp BR, Boorjian SA, De Langhe SP, Erickson LA, Sharma V, Cheville JC, Leibovich BC. Renal Neoplasia in Birt-Hogg-Dube Syndrome: Integrated Histopathologic, Bulk, and Single-cell Transcriptomic Analysis. Eur Urol. 2025 Apr 18 [Epub ahead of print]
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  4. Al-Kateb H, Knight SM, Sivasankaran G, Voss JS, Pitel BA, Blommel JH, Jerde CR, Rumilla KM, Lee JL, Mattson NR, Lauer KP, Zimmerman Zuckerman EA, Hofich CD, Milosevic D, Thompson J, Tillmans LS, Stai TT, Dasari S, Pryzbylski AL, Mullineaux LG, Ida CM, Jenkins RB, Gupta S, Kipp BR, Halling KC. Clinical Validation of the TruSight Oncology 500 Assay for the Detection and Reporting of Pan-Cancer Biomarkers. J Mol Diagn. 2025 Apr; 27 (4):292-305 Epub 2025 Jan 31
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  5. Ham H, Isham CR, Ristagno EH, Correia C, Ennis SM, Kandasamy RK, Garapati K, Zhang C, Kohlhagen MC, Sadighi Akha E, Rodriguez-Quevedo MF, Schultz DF, Chen B, Boyce TG, Gregory SW, Kohorst MA, Dasari S, Murray DL, Halling KC, Kipp BR, Kumánovics A, Li H, Pandey A, Billadeau DD, Sadighi Akha AA. A novel dominant-negative variant of IRF8 in a mother and son: Clinical, phenotypic and biological characteristics. J Allergy Clin Immunol. 2025 Mar 08. [Epub ahead of print]
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  6. Tekin B, Folpe AL, Dasari S, Hofich CD, McCarthy M, Alvand S, Pujari GP, Halling KC, Cheville JC, Whaley RD, Gupta S. TFE3-rearranged ossifying fibromyxoid tumors are uniquely negative for glycoprotein non-metastatic melanoma protein B: A study of 13 TFE3-rearranged mesenchymal tumors. Hum Pathol. 2025 Mar; 157:105768 Epub 2025 Apr 04
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  7. Atiq MA, Balan J, Blackburn PR, Gross JM, Voss JS, Jin L, Fadra N, Davila JI, Pitel BA, Siqueira Parrilha Terra SB, Minn KT, Jackson RA, Hofich CD, Willkomm KS, Peterson BJ, Clausen SN, Rumilla KM, Gupta S, Lo YC, Ida CM, Molligan JF, Thangaiah JJ, Petersen MJ, Sukov WR, Guo R, Giannini C, Schoolmeester JK 2nd, Fritchie K, Inwards CY, Folpe AL, Oliveira AM, Torres-Mora J, Kipp BR, Halling KC. SARCP, a Clinical Next-Generation Sequencing Assay for the Detection of Gene Fusions in Sarcomas: A Description of the First 652 Cases. J Mol Diagn. 2025 Jan; 27 (1):74-95 Epub 2024 Nov 07
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  8. Thellman C, Halling KC, Saglam O. NTRK fusion cervical sarcoma with rhabdoid cells and misleading molecular testing. Histopathology. 2024 Dec; 85 (6):959-961 Epub 2024 Aug 21
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  9. Dehner CA, Buehler D, Hofich C, Halling KC, Folpe AL. Novel HMGA2::COL14A1 Fusion Identified in Xanthogranulomatous Epithelial Tumor/Keratin-Positive Giant Cell Tumor. Genes Chromosomes Cancer. 2024 Nov; 63 (11):e70010
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  10. Nguyen AJ, Johnson E, Camilleri M, Wieland C, Lehman JS, Agrawal S, Comfere N, Fadra N, Knudson RA, Greipp P, Halling K, Ray Guo R. Ancillary immunohistochemical and molecular testing in the classification of cutaneous sweat gland/duct neoplasms: A validation study with emphasis on histomorphologic correlation and pathological diagnosis. Hum Pathol. 2024 Aug; 150:1-8. Epub 2024 Jun 12.
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  11. Dehner CA, Johnson EF, Wieland CN, Camilleri MJ, Kajdacsy-Balla A, Oliveira AM, Halling KC, Gupta S, Guo R. Fusion-driven cutaneous and superficial mesenchymal and adnexal tumors-A clinicopathologic and molecular study of 15 cases, including a novel case of ACTB::ZMIZ2-rearranged adnexal carcinoma. J Cutan Pathol. 2024 Jul; 51 (7):538-548 Epub 2024 Mar 31
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  12. Bridge JA, Halling KC, Moncur JT, Souers RJ, Hameed MR, Fernandes H, Roy A, Surrey L, Tafe LJ, Vasalos P, Lopez-Terrada DH. RNA Sequencing for Solid Tumor Fusion Gene Detection: Proficiency Testing Practice and Performance Comparison. Arch Pathol Lab Med. 2024 May 1; 148 (5):538-544
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  13. Dasari S, McCarthy MR, Wojcik AA, Pitel BA, Samaddar A, Tekin B, Whaley RD, Raghunathan A, Hernandez LH, Jimenez RE, Stish BJ, Thompson RH, Leibovich BC, Boorjian SA, Jeffrey Karnes R, Childs DS, Quevedo JF, Kwon ED, Pagliaro LC, Costello BA, Halling KC, Cheville JC, Kipp BR, Gupta S. Genomic attributes of prostate cancer across primary and metastatic noncastrate and castrate resistant disease states: a next generation sequencing study of 183 patients. Prostate Cancer Prostatic Dis. 2024 Feb 27. [Epub ahead of print]
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  14. Dehner CA, Torres-Mora J, Gupta S, Kipp BR, Halling KC, Chen S, Warmke LM, Michal M, Alani A, Yu W, Kovacs K, Obeidin F, Iwenofu OH, Satturwar S, Meis JM, Folpe AL. Sarcomas Harboring EWSR1::PATZ1 Fusions: A Clinicopathologic Study of 17 Cases. Mod Pathol. 2024 Feb; 37 (2):100400 Epub 2023 Dec 01
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  15. Koshyk O, Dehner CA, van den Hout MFCM, Bempt IV, Sciot R, Huang HY, Agaimy A, Din NU, Klubickova N, Mosaieby E, Skalova A, Michalova K, Schoffski P, Oliveira AM, Halling KC, Gupta S, Gross JM, Nin JWM, Michal M, Folpe AL, Kosemehmetoglu K, Torres-Mora J, Michal M. EWSR1::POU2AF3(COLCA2) Sarcoma: An Aggressive, Polyphenotypic Sarcoma With a Head and Neck Predilection. Mod Pathol. 2023 Dec; 36 (12):100337 Epub 2023 Sept 22
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  16. Dehner CA, Broski SM, Meis JM, Murugan P, Chrisinger JSA, Sosa C, Petersen M, Halling KC, Gupta S, Folpe AL. Fusion-driven Spindle Cell Rhabdomyosarcomas of Bone and Soft Tissue: A Clinicopathologic and Molecular Genetic Study of 25 Cases. Mod Pathol. 2023 Oct; 36 (10):100271 Epub 2023 July 07
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  17. Chatzopoulos K, Davila JI, Fadra N, Jackson RA, Minn KT, Sotiriou S, Oliveira AM, Erickson LA, Halling KC, Rumilla KM, Rivera M. Transcriptomic and immunophenotypic characterization of two cases of adamantinoma-like Ewing sarcoma of the thyroid gland. Histopathology. 2023 Sep; 83 (3):426-434 Epub 2023 May 17
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  18. McCarthy MR, Nichols PE, Sharma V, Stanton ML, Reynolds JP, Pitel BA, Halling KC, Lohse CM, Herrera-Hernandez L, Thompson RH, Leibovich BC, Jimenez RE, Boorjian SA, Cheville JC, Gupta S. Molecular and Immunophenotypic Correlates of Metastatic Epithelioid Angiomyolipoma Include Alterations of TP53, RB1, and ATRX. Arch Pathol Lab Med. 2023 Jul 01; 147(7):817-825.
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  19. Ulici V, Hornick JL, Davis JL, Mehrotra S, Meis JM, Halling KC, Fletcher CDM, Kao E, Folpe AL. Extraenteric Malignant Gastrointestinal Neuroectodermal Tumor-A Clinicopathologic and Molecular Genetic Study of 11 Cases. Mod Pathol. 2023 Jul; 36 (7):100160 Epub 2023 Mar 17
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  20. Gonzalez-Bosquet J, Weroha SJ, Bakkum-Gamez JN, Weaver AL, McGree ME, Dowdy SC, Famuyide AO, Kipp BR, Halling KC, Yadav S, Couch FJ, Podratz KC. Prognostic stratification of endometrial cancers with high microsatellite instability or no specific molecular profile. Front Oncol. 2023; 13:1105504. Epub 2023 May 23.
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  21. Dimou A, Lo YC, Merrell KW, Halling KC, Mansfield AS. Small Cell Transformation in a Patient With RET Fusion-Positive Lung Adenocarcinoma on Pralsetinib. JCO Precis Oncol. 2022 Dec; 6:e2200478
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  22. Ji H, Barr Fritcher EG, Yin J, Bainter TM, Zemla TJ, Gores GJ, Halling KC, Kipp BR, Roberts LR. Evaluating the Significance of Pancreatobiliary Fluorescence In Situ Hybridization Polysomy on Prognosis in De Novo Cholangiocarcinoma. Clin Transl Gastroenterol. 2022 Oct 1; 13 (10):e00523 Epub 2022 Oct 01
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  23. Dashti NK, Dermawan JK, Schoolmeester JK, Halling KC, Antonescu CR. A novel WWTR1::AFF2 fusion in an intra-abdominal soft tissue sarcoma with associated endometriosis. Genes Chromosomes Cancer. 2022 Aug; 61 (8):497-502 Epub 2022 Apr 26
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  24. Zimmerman Zuckerman E, Thompson JA, Schneider AR, Campion MB, Johns JJ, Stier TJ, Peterson LM, Ward AM, Blommel JH, Gnanaolivu RD, Lauer KP, Sivasankaran G, Balan J, Dasari S, Sakai Y, Marcou CA, Zheng G, Halling KC, Shen W, Viswanatha DS, Niu Z. Automation of hybridization and capture based next generation sequencing library preparation requires reduction of on-deck bead binding and heated wash temperatures. SLAS Technol. 2022 Jun; 27 (3):214-218 Epub 2021 Nov 26
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  25. Rahi H, Olave MC, Fritchie KJ, Greipp PT, Halling KC, Kipp BR, Graham RP. Gene fusions in gastrointestinal tract cancers. Genes Chromosomes Cancer. 2022 May; 61(5):285-297.
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  26. Gonzalez-Bosquet J, Weroha SJ, Bakkum-Gamez JN, Weaver AL, McGree ME, Dowdy SC, Famuyide AO, Kipp BR, Halling KC, Yadav S, Couch FJ, Podratz KC. ECPPF (E2F1, CCNA2, POLE, PPP2R1A, FBXW7) stratification: Profiling high-risk subtypes of histomorphologically low-risk and treatment-insensitive endometrioid endometrial cancer. PLoS One. 2022; 17(12):e0278408. Epub 2022 Dec 01.
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  27. Gupta S, Erickson LA, Lohse CM, Shen W, Pitel BA, Knight SM, Halling KC, Herrera-Hernandez L, Boorjian SA, Thompson RH, Leibovich BC, Jimenez RE, Cheville JC. Assessment of Risk of Hereditary Predisposition in Patients With Melanoma and/or Mesothelioma and Renal Neoplasia. JAMA Netw Open. 2021 Nov 1; 4 (11):e2132615 Epub 2021 Nov 01
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  28. Schoolmeester JK, Folpe AL, Nair AA, Halling K, Sutton BC, Landers E, Karnezis AN, Dickson BC, Nucci MR, Kolin DL. EWSR1-WT1 gene fusions in neoplasms other than desmoplastic small round cell tumor: a report of three unusual tumors involving the female genital tract and review of the literature. Mod Pathol. 2021 Oct; 34 (10):1912-1920 Epub 2021 June 07
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  29. Ida CM, Johnson DR, Nair AA, Davila J, Kollmeyer TM, Minn K, Fadra NM, Balcom JR, Fung KA, Kim DK, Kaufmann TJ, Kipp BR, Halling KC, Jenkins RB, Giannini C. Polymorphous Low-Grade Neuroepithelial Tumor of the Young (PLNTY): Molecular Profiling Confirms Frequent MAPK Pathway Activation. J Neuropathol Exp Neurol. 2021 Sep 27; 80 (9):821-829
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  30. Van Treeck BJ, Thangaiah JJ, Torres-Mora J, Stevens TM, Rothermundt C, Fassan M, Loupakis F, Diebold J, Hornick JL, Halling KC, Folpe AL. NUTM1-rearranged colorectal sarcoma: a clinicopathologically and genetically distinctive malignant neoplasm with a poor prognosis. Mod Pathol. 2021 Aug; 34 (8):1547-1557 Epub 2021 Mar 13
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  31. Gonzalez-Bosquet J, Bakkum-Gamez JN, Weaver AL, McGree ME, Dowdy SC, Famuyide AO, Kipp BR, Halling KC, Couch FJ, Podratz KC. PP2A and E3 ubiquitin ligase deficiencies: Seminal biological drivers in endometrial cancer. Gynecol Oncol. 2021 Jul; 162 (1):182-189 Epub 2021 Apr 16
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  32. DiGuardo MA, Davila JI, Jackson RA, Nair AA, Fadra N, Minn KT, Atiq MA, Zarei S, Blommel JH, Knight SM, Jen J, Eckloff BW, Voss JS, Rumilla KM, Kerr SE, Lam-Himlin DM, Bellizzi AM, Graham RP, Kipp BR, Jenkins RB, Halling KC. RNA-Seq Reveals Differences in Expressed Tumor Mutation Burden in Colorectal and Endometrial Cancers with and without Defective DNA-Mismatch Repair. J Mol Diagn. 2021 May; 23(5):555-564. Epub 2021 Feb 04.
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  33. Murray JD, Willrich MA, Krowka MJ, Bobr A, Murray DL, Halling KC, Graham RP, Snyder MR. Liquid Chromatography-Tandem Mass Spectrometry-Based alpha1-Antitrypsin (AAT) Testing. Am J Clin Pathol. 2021 Mar 15; 155 (4):547-552
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  34. Mujahed T, Tazelaar HD, Sukov WR, Halling KC, Davila JI, Glass C, Pavlisko EN, Strickland KC, Roggli V, Haque M, Mneimneh W, Carter E, Galateau-Salle F, Glidden D, Garcia-Kennedy R, Larsen BT. Malignant Peritoneal Mesothelioma Arising in Young Adults With Long-standing Indwelling Intra-abdominal Shunt Catheters. Am J Surg Pathol. 2021 Feb 1; 45 (2):255-262
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  35. Zhao Y, Yu H, Ida CM, Halling KC, Kipp BR, Geiersbach K, Rumilla KM, Gupta S, Lin MT, Zheng G. Assessment of RAS Dependency for BRAF Alterations Using Cancer Genomic Databases. JAMA Netw Open. 2021 Jan 04; 4(1):e2035479.
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  36. Balan J, Jenkinson G, Nair A, Saha N, Koganti T, Voss J, Zysk C, Barr Fritcher EG, Ross CA, Giannini C, Raghunathan A, Kipp BR, Jenkins R, Ida C, Halling KC, Blackburn PR, Dasari S, Oliver GR, Klee EW. SeekFusion - A Clinically Validated Fusion Transcript Detection Pipeline for PCR-Based Next-Generation Sequencing of RNA. Front Genet. 2021; 12:739054. Epub 2021 Oct 22.
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  37. Bosquet JG, Zhang Q, Cliby WA, Bakkum-Gamez JN, Cen L, Dowdy SC, Sherman ME, Weroha SJ, Clayton AC, Kipp BR, Halling KC, Couch FJ, Podratz KC. Association of a novel endometrial cancer biomarker panel with prognostic risk, platinum insensitivity, and targetable therapeutic options. PLoS One. 2021; 16 (1):e0245664 Epub 2021 Jan 27
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  38. Gleeson FC, Levy MJ, Jackson RA, Murphy SJ, Halling KC, Kipp BR, Graham RP, Zhang L. Lipocalin-2 Expression in Pancreas Adenocarcinoma Tumor Microenvironment Via Endoscopic Ultrasound Fine Needle Biopsy Is Feasible and May Reveal a Therapeutic Target. Pancreas 2020 Nov/Dec; 49 (10):e98-e99
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  39. Shah KK, Neff JL, Erickson LA, Jackson RA, Jenkins SM, Mansfield AS, Moser JC, Harris AL, Copland JA, Halling KC, Flotte TJ. Correlation of novel ALK(ATI) with ALK immunohistochemistry and clinical outcomes in metastatic melanoma. Histopathology. 2020 Oct; 77 (4):601-610 Epub 2020 Sept 15
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  40. Fritchie KJ, Torres-Mora J, Inwards C, Thway K, Vaiyapuri S, Jackson R, Minn K, Halling K, Arndt C, Houdek MT, Wenger DE, Curry R, Thirumala S, Fisher C, Davila J, Folpe AL. Xanthogranulomatous epithelial tumor: report of 6 cases of a novel, potentially deceptive lesion with a predilection for young women. Mod Pathol. 2020 Oct; 33 (10):1889-1895 Epub 2020 May 15
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  41. Cheek EH, Fadra N, Jackson RA, Davila JI, Sukov WR, Uckerman MT, Clayton A, Keeney GL, Halling KC, Torres-Mora J, Schoolmeester JK. Uterine inflammatory myofibroblastic tumors in pregnant women with and without involvement of the placenta: a study of 6 cases with identification of a novel TIMP3-RET fusion. Hum Pathol. 2020 Mar; 97:29-39 Epub 2020 Jan 07
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  42. Gleeson FC, Levy MJ, Jackson RA, Murphy SJ, Halling KC, Kipp BR, Graham RP, Zhang L. Endoscopic ultrasound may be used to deliver gene expression signatures using digital mRNA detection methods to immunophenotype pancreatic ductal adenocarcinoma to facilitate personalized immunotherapy. Pancreatology. 2020 Mar; 20 (2):229-238 Epub 2019 Dec 05
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  43. Anagnostou T, Knudson RA, Pearce KE, Meyer RG, Pitel BA, Peterson JF, Baughn LB, Reichard KK, Ketterling RP, Kloft-Nelson SM, Knutson DL, Khan SP, Gangat N, Litzow MR, Hogan WJ, Wolanskyj A, Al-Kali A, Begna KH, Elliott M, Pardanani A, Foran J, Shah M, Tefferi A, Alkhateeb H, Halling K, Rodriguez V, Greipp PT, Patnaik MM. Clinical utility of fluorescence in situ hybridization-based diagnosis of BCR-ABL1 like (Philadelphia chromosome like) B-acute lymphoblastic leukemia. Am J Hematol 2020 Mar; 95 (3):E68-E72 Epub 2020 Jan 26
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  44. Blessing MM, Blackburn PR, Krishnan C, Harrod VL, Barr Fritcher EG, Zysk CD, Jackson RA, Milosevic D, Nair AA, Davila JI, Balcom JR, Jenkins RB, Halling KC, Kipp BR, Nageswara Rao AA, Laack NN, Daniels DJ, Macon WR, Ida CM. Desmoplastic Infantile Ganglioglioma: A MAPK Pathway-Driven and Microglia/Macrophage-Rich Neuroepithelial Tumor. J Neuropathol Exp Neurol. 2019 Nov 1; 78 (11):1011-1021
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  45. Blackburn PR, Davila JI, Jackson RA, Fadra N, Atiq MA, Pitel BA, Nair AA, VanDeWalker TJ, Hessler MG, Hovel SK, Wehrs RN, Fritchie KJ, Jenkins RB, Halling KC, Geiersbach KB. RNA sequencing identifies a novel USP9X-USP6 promoter swap gene fusion in a primary aneurysmal bone cyst. Genes Chromosomes Cancer. 2019 Aug; 58(8):589-594. Epub 2019 Mar 06.
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  46. Sonbol MB, Halling KC, Douglas DD, Ross HJ. A Case of Donor-Transmitted Non-Small Cell Lung Cancer After Liver Transplantation: An Unwelcome Guest. Oncologist. 2019 Jun; 24 (6):e391-e393 Epub 2019 Feb 12
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  47. Ainsworth AJ, Dashti NK, Mounajjed T, Fritchie KJ, Davila J, Mopuri R, Jackson RA, Halling KC, Bakkum-Gamez JN, Schoolmeester JK. Leiomyoma with KAT6B-KANSL1 fusion: case report of a rapidly enlarging uterine mass in a postmenopausal woman. Diagn Pathol. 2019 Apr 25; 14 (1):32
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  48. Lotfalla MM, Folpe AL, Fritchie KJ, Greipp PT, Galliano GG, Halling KC, Mounajjed T, Torres-Mora J, Graham RP. Hepatic YAP1-TFE3 Rearranged Epithelioid Hemangioendothelioma. Case Rep Gastrointest Med. 2019; 2019:7530845 Epub 2019 June 23
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  49. Milosevic D, Mills JR, Campion MB, Vidal-Folch N, Voss JS, Halling KC, Highsmith WE, Liu MC, Kipp BR, Grebe SKG. Applying Standard Clinical Chemistry Assay Validation to Droplet Digital PCR Quantitative Liquid Biopsy Testing. Clin Chem. 2018 Dec; 64 (12):1732-1742 Epub 2018 Sept 20
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  50. Dashti NK, Wehrs RN, Thomas BC, Nair A, Davila J, Buckner JC, Martinez AP, Sukov WR, Halling KC, Howe BM, Folpe AL. Spindle cell rhabdomyosarcoma of bone with FUS-TFCP2 fusion: confirmation of a very recently described rhabdomyosarcoma subtype. Histopathology. 2018 Sep; 73(3):514-520. Epub 2018 Jun 29.
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  51. Winters JL, Davila JI, McDonald AM, Nair AA, Fadra N, Wehrs RN, Thomas BC, Balcom JR, Jin L, Wu X, Voss JS, Klee EW, Oliver GR, Graham RP, Neff JL, Rumilla KM, Aypar U, Kipp BR, Jenkins RB, Jen J, Halling KC. Development and Verification of an RNA Sequencing (RNA-Seq) Assay for the Detection of Gene Fusions in Tumors. J Mol Diagn. 2018 Jul; 20(4):495-511. Epub 2018 Jun 19.
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  52. Mansfield AS, Ren H, Sutor S, Sarangi V, Nair A, Davila J, Elsbernd LR, Udell JB, Dronca RS, Park S, Markovic SN, Sun Z, Halling KC, Nevala WK, Aubry MC, Dong H, Jen J. Contraction of T cell richness in lung cancer brain metastases. Sci Rep. 2018 Feb 1; 8 (1):2171 Epub 2018 Feb 01
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  53. Poneros JM, Faye AS, Barr Fritcher EG, Sen A, Anandasabapathy S, Bresalier RS, Marcon N, Turgeon DK, Appelman H, Normolle D, Morrison LE, Brenner DE, Halling KC. A Multicenter Study of a Fluorescence In Situ Hybridization Probe Set for Diagnosing High-Grade Dysplasia and Adenocarcinoma in Barrett's Esophagus. Dig Dis Sci. 2017 May; 62 (5):1216-1222 Epub 2017 Mar 06
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  54. Davila JI, Fadra NM, Wang X, McDonald AM, Nair AA, Crusan BR, Wu X, Blommel JH, Jen J, Rumilla KM, Jenkins RB, Aypar U, Klee EW, Kipp BR, Halling KC. Impact of RNA degradation on fusion detection by RNA-seq. BMC Genomics. 2016 Oct 20; 17(1):814.
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  55. Brankley SM, Halling KC, Jenkins SM, Timmer MR, Iyer PG, Smyrk TC, Barr Fritcher EG, Voss JS, Kipp BR, Campion MB, Lutzke LS, Minot DM, Wang KK. Fluorescence in situ hybridization identifies high risk Barrett's patients likely to develop esophageal adenocarcinoma. Dis Esophagus. 2016 Aug; 29 (6):513-9 Epub 2015 June 05
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  56. Chaiteerakij R, Barr Fritcher EG, Angsuwatcharakon P, Ridtitid W, Chaithongrat S, Leerapun A, Baron TH, Kipp BR, Henry MR, Halling KC, Rerknimitr R, Roberts LR. Fluorescence in situ hybridization compared with conventional cytology for the diagnosis of malignant biliary tract strictures in Asian patients. Gastrointest Endosc. 2016 Jun; 83 (6):1228-35 Epub 2015 Dec 10
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  57. Yang JD, Campion MB, Liu MC, Chaiteerakij R, Giama NH, Ahmed Mohammed H, Zhang X, Hu C, Campion VL, Jen J, Venkatesh SK, Halling KC, Kipp BR, Roberts LR. Circulating tumor cells are associated with poor overall survival in patients with cholangiocarcinoma. Hepatology. 2016 Jan; 63 (1):148-58 Epub 2015 Aug 07
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  58. Carpenter JE, Clayton AC, Halling KC, Bonthius DJ, Buckingham EM, Jackson W, Dotzler SM, Card JP, Enquist LW, Grose C. Defensive Perimeter in the Central Nervous System: Predominance of Astrocytes and Astrogliosis during Recovery from Varicella-Zoster Virus Encephalitis. J Virol. 2016 Jan 1; 90 (1):379-91 Epub 2015 Oct 21
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  59. Barr Fritcher EG, Voss JS, Brankley SM, Campion MB, Jenkins SM, Keeney ME, Henry MR, Kerr SM, Chaiteerakij R, Pestova EV, Clayton AC, Zhang J, Roberts LR, Gores GJ, Halling KC, Kipp BR. An Optimized Set of Fluorescence In Situ Hybridization Probes for Detection of Pancreatobiliary Tract Cancer in Cytology Brush Samples. Gastroenterology. 2015 Dec; 149 (7):1813-1824.e1 Epub 2015 Aug 29
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  60. Graham RP, Dina MA, Howe SC, Butz ML, Willkomm KS, Murray DL, Snyder MR, Rumilla KM, Halling KC, Highsmith WE Jr. SERPINA1 Full-Gene Sequencing Identifies Rare Mutations Not Detected in Targeted Mutation Analysis. J Mol Diagn. 2015 Nov; 17 (6):689-94 Epub 2015 Aug 28
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  61. Graham RP, Kerr SE, Butz ML, Thibodeau SN, Halling KC, Smyrk TC, Dina MA, Waugh VM, Rumilla KM. Heterogenous MSH6 loss is a result of microsatellite instability within MSH6 and occurs in sporadic and hereditary colorectal and endometrial carcinomas. Am J Surg Pathol. 2015 Oct; 39: (10)1370-6.
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  62. Graham RP, Jin L, Knutson DL, Kloft-Nelson SM, Greipp PT, Waldburger N, Roessler S, Longerich T, Roberts LR, Oliveira AM, Halling KC, Schirmacher P, Torbenson MS. DNAJB1-PRKACA is specific for fibrolamellar carcinoma. Mod Pathol. 2015 Jun; 28(6):822-9. Epub 2015 Feb 20.
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  63. Mackenzie R, Kommoss S, Winterhoff BJ, Kipp BR, Garcia JJ, Voss J, Halling K, Karnezis A, Senz J, Yang W, Prigge ES, Reuschenbach M, Doeberitz MV, Gilks BC, Huntsman DG, Bakkum-Gamez J, McAlpine JN, Anglesio MS. Targeted deep sequencing of mucinous ovarian tumors reveals multiple overlapping RAS-pathway activating mutations in borderline and cancerous neoplasms. BMC Cancer. 2015 May 19; 15:415
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  64. Bakkum-Gamez JN, Wentzensen N, Maurer MJ, Hawthorne KM, Voss JS, Kroneman TN, Famuyide AO, Clayton AC, Halling KC, Kerr SE, Cliby WA, Dowdy SC, Kipp BR, Mariani A, Oberg AL, Podratz KC, Shridhar V, Sherman ME. Detection of endometrial cancer via molecular analysis of DNA collected with vaginal tampons. Gynecol Oncol. 2015 Apr; 137 (1):14-22 Epub 2015 Feb 10
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  65. Bogani G, Liu MC, Dowdy SC, Cliby WA, Kerr SE, Kalli KR, Kipp BR, Halling KC, Campion MB, Mariani A. Detection of circulating tumor cells in high-risk endometrial cancer. Anticancer Res. 2015 Feb; 35(2):683-7.
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  66. Eaton JE, Barr Fritcher EG, Gores GJ, Atkinson EJ, Tabibian JH, Topazian MD, Gossard AA, Halling KC, Kipp BR, Lazaridis KN. Biliary multifocal chromosomal polysomy and cholangiocarcinoma in primary sclerosing cholangitis. Am J Gastroenterol. 2015 Feb; 110 (2):299-309 Epub 2015 Jan 27
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  67. Timmer MR, Brankley SM, Gorospe EC, Sun G, Lutzke LS, Iyer PG, Halling KC, Krishnadath KK, Wang KK. Prediction of response to endoscopic therapy of Barrett's dysplasia by using genetic biomarkers. Gastrointest Endosc. 2014 Dec; 80 (6):984-91 Epub 2014 July 29
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  68. Barr Fritcher EG, Kipp BR, Halling KC, Clayton AC. FISHing for pancreatobiliary tract malignancy in endoscopic brushings enhances the sensitivity of routine cytology. Cytopathology. 2014 Oct; 25(5):288-301. Epub 2014 Jul 30.
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  69. Kerr SE, Barr Fritcher EG, Campion MB, Voss JS, Kipp BR, Halling KC, Lewis JT. Biliary dysplasia in primary sclerosing cholangitis harbors cytogenetic abnormalities similar to cholangiocarcinoma. Hum Pathol. 2014 Sep; 45 (9):1797-804 Epub 2014 June 04
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  70. Graham RP, Barr Fritcher EG, Pestova E, Schulz J, Sitailo LA, Vasmatzis G, Murphy SJ, McWilliams RR, Hart SN, Halling KC, Roberts LR, Gores GJ, Couch FJ, Zhang L, Borad MJ, Kipp BR. Fibroblast growth factor receptor 2 translocations in intrahepatic cholangiocarcinoma. Hum Pathol. 2014 Aug; 45(8):1630-8. Epub 2014 Apr 13.
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  71. Reynolds JP, Voss JS, Kipp BR, Karnes RJ, Nassar A, Clayton AC, Henry MR, Sebo TJ, Zhang J, Halling KC. Comparison of urine cytology and fluorescence in situ hybridization in upper urothelial tract samples. Cancer Cytopathol. 2014 Jun; 122(6):459-67. Epub 2014 Mar 06.
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  72. Boyle TA, Bridge JA, Sabatini LM, Nowak JA, Vasalos P, Jennings LJ, Halling KC, College of American Pathologists Molecular Oncology Committee. Summary of microsatellite instability test results from laboratories participating in proficiency surveys: proficiency survey results from 2005 to 2012. Arch Pathol Lab Med. 2014 Mar; 138 (3):363-70
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  73. Reynolds JP, Voss JS, Brankley SM, Caudill JM, Henry MR, Clayton AC, Halling KC, Nassar A. Diagnostic accuracy of bronchial brush cytology and the added value of immunohistochemistry and fluorescence in situ hybridization of pulmonary neuroendocrine tumors. Cytojournal. 2014; 11:32. Epub 2014 Dec 03.
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  74. Voss JS, Iqbal S, Jenkins SM, Henry MR, Clayton AC, Jett JR, Kipp BR, Halling KC, Maldonado F. Development of a multivariate model to predict the likelihood of carcinoma in patients with indeterminate peripheral lung nodules after a nondiagnostic bronchoscopic evaluation. Hum Pathol. 2014 Jan; 45(1):41-7. Epub 2013 Oct 16
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  75. Barr Fritcher EG, Voss JS, Jenkins SM, Lingineni RK, Clayton AC, Roberts LR, Halling KC, Talwalkar JA, Gores GJ, Kipp BR. Primary sclerosing cholangitis with equivocal cytology: fluorescence in situ hybridization and serum CA 19-9 predict risk of malignancy. Cancer Cytopathol. 2013 Dec; 121(12):708-17. Epub 2013 Jul 09.
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  76. Kipp BR, Barr Fritcher EG, Pettengill JE, Halling KC, Clayton AC. Improving the accuracy of pancreatobiliary tract cytology with fluorescence in situ hybridization: a molecular test with proven clinical success. Cancer Cytopathol. 2013 Nov; 121(11):610-9. Epub 2013 Apr 30.
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  77. Viray H, Li K, Long TA, Vasalos P, Bridge JA, Jennings LJ, Halling KC, Hameed M, Rimm DL. A prospective, multi-institutional diagnostic trial to determine pathologist accuracy in estimation of percentage of malignant cells. Arch Pathol Lab Med. 2013 Nov; 137: (11)1545-9.
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  78. Kerr SE, Flotte AB, McFalls MJ, Vrana JA, Halling KC, Bell DA. Matching maternal isodisomy in mucinous carcinomas and associated ovarian teratomas provides evidence of germ cell derivation for some mucinous ovarian tumors. Am J Surg Pathol. 2013 Aug; 37(8):1229-35.
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  79. Voss JS, Holtegaard LM, Kerr SE, Fritcher EG, Roberts LR, Gores GJ, Zhang J, Highsmith WE, Halling KC, Kipp BR. Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions. Hum Pathol. 2013 Jul; 44 (7):1216-22 Epub 2013 Feb 04
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  80. Brick KE, Halling KC, Khan YK, Peters MS. BRAF mutation-positive folliculotropic metastatic melanoma. Am J Dermatopathol. 2013 Jul; 35 (5):609-12
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  81. van den Bent MJ, Hartmann C, Preusser M, Strobel T, Dubbink HJ, Kros JM, von Deimling A, Boisselier B, Sanson M, Halling KC, Diefes KL, Aldape K, Giannini C. Interlaboratory comparison of IDH mutation detection. J Neurooncol. 2013 Apr; 112(2):173-8. Epub 2013 Jan 29.
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  82. Kerr SE, Thomas CB, Thibodeau SN, Ferber MJ, Halling KC. APC germline mutations in individuals being evaluated for familial adenomatous polyposis: a review of the Mayo Clinic experience with 1591 consecutive tests. J Mol Diagn. 2013 Jan; 15(1):31-43. Epub 2012 Nov 14.
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  83. Kipp BR, Voss JS, Kerr SE, Barr Fritcher EG, Graham RP, Zhang L, Highsmith WE, Zhang J, Roberts LR, Gores GJ, Halling KC. Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma. Hum Pathol. 2012 Oct; 43 (10):1552-8 Epub 2012 Apr 12
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  84. Bakkum-Gamez JN, Chien J, Clayton AC, Halling KC, Cliby WA, Dowdy SC, Kipp BR, Famuyide A, Mariani A, Oberg AL, Wentzensen N, Sherman M, Podratz KC, Shridhar V. Development of biomarkers in endometrial cancer and its precursor lesions. J Womens Health. 2012 Oct; 21(10):1004.
  85. Ida CM, Lambert SR, Rodriguez FJ, Voss JS, Mc Cann, Mc Cann BE, Seys AR, Halling KC, Collins VP, Giannini C. BRAF alterations are frequent in cerebellar low-grade astrocytomas with diffuse growth pattern. J Neuropathol Exp Neurol. 2012 Jul; 71 (7):631-9
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  86. Peterson LM, Kipp BR, Halling KC, Kerr SE, Smith DI, Distad TJ, Clayton AC, Medeiros F. Molecular characterization of endometrial cancer: a correlative study assessing microsatellite instability, MLH1 hypermethylation, DNA mismatch repair protein expression, and PTEN, PIK3CA, KRAS, and BRAF mutation analysis. Int J Gynecol Pathol. 2012 May; 31 (3):195-205
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  87. Levy MJ, Oberg TN, Campion MB, Clayton AC, Halling KC, Henry MR, Kipp BR, Sebo TJ, Zhang J, Enders FT, Clain JE, Gleeson FC, Rajan E, Roberts LR, Topazian MD, Wang KK, Gores GJ. Comparison of methods to detect neoplasia in patients undergoing endoscopic ultrasound-guided fine-needle aspiration. Gastroenterology. 2012 May; 142(5):1112-1121.e2. Epub 2012 Feb 07.
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  88. Sethi S, Simonetto DA, Abdelmoneim SS, Campion MB, Kaloiani I, Clayton AC, Kremers WK, Halling KC, Kamath PS, Talwalkar J, Shah VH. Comparison of circulating endothelial cell/platelet count ratio to aspartate transaminase/platelet ratio index for identifying patients with cirrhosis. J Clin Exp Hepatol. 2012 Mar; 2 (1):19-26 Epub 2012 Apr 12
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  89. Brankley SM, Fritcher EG, Smyrk TC, Keeney ME, Campion MB, Voss JS, Clayton AC, Wang KK, Lutzke LS, Kipp BR, Halling KC. Fluorescence in situ hybridization mapping of esophagectomy specimens from patients with Barrett's esophagus with high-grade dysplasia or adenocarcinoma. Hum Pathol. 2012 Feb; 43(2):172-9. Epub 2011 Aug 04.
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  90. Kane LE, Root RR, Voss JS, Caudill JL, Sorenson AM, Colborn LK, Halling KC, Henry MR, Clayton AC, Kipp BR. Molecular diagnostics, personalized medicine, and the evolving role of the cytotechnologist: an institutional experience. Acta Cytol. 2012; 56(6):678-85. Epub 2012 Nov 24.
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  91. Halling KC, Schrijver I, Persons DL. Test verification and validation for molecular diagnostic assays. Arch Pathol Lab Med. 2012 Jan; 136(1):11-3.
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  92. Kamel-Reid S, Zhang T, Persons DL, Nikiforova MN, Halling KC, Molecular Oncology Resource Committee of the College of American Pathologists. Validation of KRAS testing for anti-EGFR therapeutic decisions for patients with metastatic colorectal carcinoma. Arch Pathol Lab Med. 2012 Jan; 136(1):26-32.
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  93. Jennings LJ, Smith FA, Halling KC, Persons DL, Kamel-Reid S, Molecular Oncology Resource Committee of the College of American Pathologists. Design and analytic validation of BCR-ABL1 quantitative reverse transcription polymerase chain reaction assay for monitoring minimal residual disease. Arch Pathol Lab Med. 2012 Jan; 136(1):33-40.
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  94. Barr Fritcher EG, Kipp BR, Voss JS, Clayton AC, Lindor KD, Halling KC, Gores GJ. Primary sclerosing cholangitis patients with serial polysomy fluorescence in situ hybridization results are at increased risk of cholangiocarcinoma. Am J Gastroenterol. 2011 Nov; 106(11):2023-8. Epub 2011 Aug 16.
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  95. Barr Fritcher EG, Caudill JL, Blue JE, Djuric K, Feipel L, Maritim BK, Ragheb AA, Halling KC, Henry MR, Clayton AC. Identification of malignant cytologic criteria in pancreatobiliary brushings with corresponding positive fluorescence in situ hybridization results. Am J Clin Pathol. 2011 Sep; 136(3):442-9.
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  96. Begum R, Harnois D, Satyanarayana R, Krishna M, Halling KC, Kim GP, Nguyen JH, Keaveny AP. Retransplantation for donor-derived neuroendocrine tumor. Liver Transpl. 2011 Jan; 17(1):83-7.
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  97. Kipp BR, Fritcher EG, Clayton AC, Gores GJ, Roberts LR, Zhang J, Levy MJ, Halling KC. Comparison of KRAS mutation analysis and FISH for detecting pancreatobiliary tract cancer in cytology specimens collected during endoscopic retrograde cholangiopancreatography. J Mol Diagn. 2010 Nov; 12(6):780-6. Epub 2010 Sep 23.
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  98. Voss JS, Kipp BR, Campion MB, Sokolova IA, Henry MR, Halling KC, Clayton AC. Assessment of fluorescence in situ hybridization and hybrid capture 2 analyses of cervical cytology specimens diagnosed as low grade squamous intraepithelial lesion for the detection of high grade cervical intraepithelial neoplasia. Anal Quant Cytol Histol. 2010 Jun; 32 (3):121-30
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  99. Levy MJ, Gleeson FC, Campion MB, Caudill JL, Clain JE, Halling K, Rajan E, Topazian MD, Wang KK, Wiersema MJ, Clayton A. Prospective cytological assessment of gastrointestinal luminal fluid acquired during EUS: a potential source of false-positive FNA and needle tract seeding. Am J Gastroenterol. 2010 Jun; 105: (6)1311-8.
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  100. Gleeson FC, Kipp BR, Caudill JL, Clain JE, Clayton AC, Halling KC, Henry MR, Rajan E, Topazian MD, Wang KK, Wiersema MJ, Zhang J, Levy MJ. False positive endoscopic ultrasound fine needle aspiration cytology: incidence and risk factors. Gut. 2010 May; 59 (5):586-93
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  101. Fritcher EG, Halling KC. Advanced cytologic approaches for the diagnosis of pancreatobiliary cancer. Curr Opin Gastroenterol. 2010 May; 26(3):259-64.
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  102. Voss JS, Kipp BR, Halling KC, Henry MR, Jett JR, Clayton AC, Rickman OB. Fluorescence in situ hybridization testing algorithm improves lung cancer detection in bronchial brushing specimens. Am J Respir Crit Care Med. 2010 Mar 1; 181(5):478-85. Epub 2009 Dec 10.
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  103. Abdelmoneim SS, Talwalkar J, Sethi S, Kamath P, Fathalla MM, Kipp BR, Campion MB, Clayton AC, Halling KC, Shah VH. A prospective pilot study of circulating endothelial cells as a potential new biomarker in portal hypertension. Liver Int. 2010 Feb; 30 (2):191-7 Epub 2009 Oct 19
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  104. Kipp BR, Ketterling RP, Oberg TN, Cousin MA, Plagge AM, Wiktor AE, Ihrke JM, Meyers CH, Morice WG, Halling KC, Clayton AC. Comparison of fluorescence in situ hybridization, p57 immunostaining, flow cytometry, and digital image analysis for diagnosing molar and nonmolar products of conception. Am J Clin Pathol. 2010 Feb; 133(2):196-204.
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  105. Bangarulingam SY, Bjornsson E, Enders F, Barr Fritcher EG, Gores G, Halling KC, Lindor KD. Long-term outcomes of positive fluorescence in situ hybridization tests in primary sclerosing cholangitis. Hepatology. 2010 Jan; 51 (1):174-80
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  106. Song M, Ruth A, Policht FA, Bubendorf L, Feichter G, Kipp BR, Halling KC, Sokolova IA. Dysplastic cells in cytological cervical samples show a high incidence of chromosomal abnormalities. Diagn Cytopathol. 2010 Jan; 38(1):28-33.
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  107. Washington MK, Berlin J, Branton P, Burgart LJ, Carter DK, Fitzgibbons PL, Halling K, Frankel W, Jessup J, Kakar S, Minsky B, Nakhleh R, Compton CC, Members of the Cancer Committee College of American Pathologists. Protocol for the examination of specimens from patients with primary carcinoma of the colon and rectum. Arch Pathol Lab Med. 2009 Oct; 133(10):1539-51.
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  108. Monzon FA, Ogino S, Hammond ME, Halling KC, Bloom KJ, Nikiforova MN. The role of KRAS mutation testing in the management of patients with metastatic colorectal cancer. Arch Pathol Lab Med. 2009 Oct; 133(10):1600-6.
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  109. Cicek MS, Slager SL, Achenbach SJ, French AJ, Blair HE, Fink SR, Foster NR, Kabat BF, Halling KC, Cunningham JM, Cerhan JR, Jenkins RB, Boardman LA, Petersen GM, Sargent DJ, Alberts SR, Limburg PJ, Thibodeau SN. Functional and clinical significance of variants localized to 8q24 in colon cancer. Cancer Epidemiol Biomarkers Prev. 2009 Sep; 18(9):2492-500. Epub 2009 Aug 18.
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  110. Voss JS, Kipp BR, Campion MB, Sokolova IA, Henry MR, Halling KC, Clayton AC. Comparison of fluorescence in situ hybridization, hybrid capture 2 and polymerase chain reaction for the detection of high-risk human papillomavirus in cervical cytology specimens. Anal Quant Cytol Histol. 2009 Aug; 31: (4)208-16.
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  111. Boland JM, Erdogan S, Vasmatzis G, Yang P, Tillmans LS, Johnson MR, Wang X, Peterson LM, Halling KC, Oliveira AM, Aubry MC, Yi ES. Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas. Hum Pathol. 2009 Aug; 40 (8):1152-8 Epub 2009 Apr 22
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  112. Fritcher EG, Kipp BR, Halling KC, Oberg TN, Bryant SC, Tarrell RF, Gores GJ, Levy MJ, Clayton AC, Sebo TJ, Roberts LR. A multivariable model using advanced cytologic methods for the evaluation of indeterminate pancreatobiliary strictures. Gastroenterology. 2009 Jun; 136(7):2180-6. Epub 2009 Feb 14.
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  113. Kipp BR, Tanasescu M, Else TA, Bryant SC, Karnes RJ, Sebo TJ, Halling KC. Quantitative fluorescence in situ hybridization and its ability to predict bladder cancer recurrence and progression to muscle-invasive bladder cancer. J Mol Diagn. 2009 Mar; 11 (2):148-54 Epub 2009 Jan 29
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  114. Kipp BR, Tyner HL, Campion MB, Voss JS, Karnes RJ, Sebo TJ, Halling KC, Zhang J. Chromosomal alterations detected by fluorescence in situ hybridization in urothelial carcinoma and rarer histologic variants of bladder cancer. Am J Clin Pathol. 2008 Oct; 130 (4):552-9
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  115. Charatcharoenwitthaya P, Enders FB, Halling KC, Lindor KD. Utility of serum tumor markers, imaging, and biliary cytology for detecting cholangiocarcinoma in primary sclerosing cholangitis. Hepatology. 2008 Oct; 48: (4)1106-17.
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  116. Halling KC, Kipp BR. Bladder cancer detection using FISH (UroVysion assay). Adv Anat Pathol. 2008 Sep; 15(5):279-86.
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  117. Voss JS, Kipp BR, Krueger AK, Clayton AC, Halling KC, Karnes RJ, Henry MR, Sebo TJ. Changes in specimen preparation method may impact urine cytologic evaluation. Am J Clin Pathol. 2008 Sep; 130(3):428-33.
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  118. Kipp BR, Medeiros F, Campion MB, Distad TJ, Peterson LM, Keeney GL, Halling KC, Clayton AC. Direct uterine sampling with the Tao brush sampler using a liquid-based preparation method for the detection of endometrial cancer and atypical hyperplasia: a feasibility study. Cancer. 2008 Aug 25; 114(4):228-35.
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  119. Fritcher EG, Brankley SM, Kipp BR, Voss JS, Campion MB, Morrison LE, Legator MS, Lutzke LS, Wang KK, Sebo TJ, Halling KC. A comparison of conventional cytology, DNA ploidy analysis, and fluorescence in situ hybridization for the detection of dysplasia and adenocarcinoma in patients with Barrett's esophagus. Hum Pathol. 2008 Aug; 39 (8):1128-35 Epub 2008 July 07
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  120. Prasad GA, Wang KK, Halling KC, Buttar NS, Wongkeesong LM, Zinsmeister AR, Brankley SM, Fritcher EG, Westra WM, Krishnadath KK, Lutzke LS, Borkenhagen LS. Utility of biomarkers in prediction of response to ablative therapy in Barrett's esophagus. Gastroenterology. 2008 Aug; 135(2):370-9. Epub 2008 May 07.
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  121. Prasad GA, Wang KK, Halling KC, Buttar NS, Wongkeesong LM, Zinsmeister AR, Brankley SM, Westra WM, Lutzke LS, Borkenhagen LS, Dunagan K. Correlation of histology with biomarker status after photodynamic therapy in Barrett esophagus. Cancer. 2008 Aug 1; 113 (3):470-6
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  122. Brankley SM, Adams EJ, Christensen MR, Everts CR, Lund JD, Oberg TN, Plagge AM, Zieman AH, Kipp BR, Halling KC. A study of the reproducibility of a fluorescence in situ hybridization bladder cancer detection assay. Anal Quant Cytol Histol. 2008 Jun; 30(3):145-51.
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  123. Levy MJ, Baron TH, Clayton AC, Enders FB, Gostout CJ, Halling KC, Kipp BR, Petersen BT, Roberts LR, Rumalla A, Sebo TJ, Topazian MD, Wiersema MJ, Gores GJ. Prospective evaluation of advanced molecular markers and imaging techniques in patients with indeterminate bile duct strictures. Am J Gastroenterol. 2008 May; 103 (5):1263-73
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  124. Kipp BR, Halling KC, Campion MB, Wendel AJ, Karnes RJ, Zhang J, Sebo TJ. Assessing the value of reflex fluorescence in situ hybridization testing in the diagnosis of bladder cancer when routine urine cytological examination is equivocal. J Urol. 2008 Apr; 179 (4):1296-301; discussion 1301 Epub 2008 Mar 04
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  125. Medeiros F, Rigl CT, Anderson GG, Becker SH, Halling KC. Tissue handling for genome-wide expression analysis: a review of the issues, evidence, and opportunities. Arch Pathol Lab Med. 2007 Dec; 131 (12):1805-16
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  126. Sokolova I, Algeciras-Schimnich A, Song M, Sitailo S, Policht F, Kipp BR, Voss JS, Halling KC, Ruth A, King W, Underwood D, Brainard J, Morrison L. Chromosomal biomarkers for detection of human papillomavirus associated genomic instability in epithelial cells of cervical cytology specimens. J Mol Diagn. 2007 Nov; 9(5):604-11.
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  127. Levy MJ, Clain JE, Clayton A, Halling KC, Kipp BR, Rajan E, Roberts LR, Root RM, Sebo TJ, Topazian MD, Wang KK, Wiersema MJ, Gores GJ. Preliminary experience comparing routine cytology results with the composite results of digital image analysis and fluorescence in situ hybridization in patients undergoing EUS-guided FNA. Gastrointest Endosc. 2007 Sep; 66 (3):483-90
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  128. Halling KC, Kipp BR. Fluorescence in situ hybridization in diagnostic cytology. Hum Pathol. 2007 Aug; 38(8):1137-44.
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  129. Barr Fritcher EG, Kipp BR, Slezak JM, Moreno-Luna LE, Gores GJ, Levy MJ, Roberts LR, Halling KC, Sebo TJ. Correlating routine cytology, quantitative nuclear morphometry by digital image analysis, and genetic alterations by fluorescence in situ hybridization to assess the sensitivity of cytology for detecting pancreatobiliary tract malignancy. Am J Clin Pathol. 2007 Aug; 128(2):272-9.
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  130. Gulley ML, Braziel RM, Halling KC, Hsi ED, Kant JA, Nikiforova MN, Nowak JA, Ogino S, Oliveira A, Polesky HF, Silverman L, Tubbs RR, Van Deerlin VM, Vance GH, Versalovic J, Molecular Pathology Resource Committee, College of American Pathologists. Clinical laboratory reports in molecular pathology. Arch Pathol Lab Med. 2007 Jun; 131(6):852-63.
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  131. DeHaan RD, Kipp BR, Smyrk TC, Abraham SC, Roberts LR, Halling KC. An assessment of chromosomal alterations detected by fluorescence in situ hybridization and p16 expression in sporadic and primary sclerosing cholangitis-associated cholangiocarcinomas. Hum Pathol. 2007 Mar; 38(3):491-9. Epub 2007 Jan 19.
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  132. Snyder MR, Katzmann JA, Butz ML, Wiley C, Yang P, Dawson DB, Halling KC, Highsmith WE, Highsmith WE, Thibodeau SN. Diagnosis of alpha-1-antitrypsin deficiency: An algorithm of quantification, genotyping, and phenotyping. Clin Chem. 2006 Dec; 52 (12):2236-42 Epub 2006 Oct 19
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  133. Moreno Luna LE, Kipp B, Halling KC, Sebo TJ, Kremers WK, Roberts LR, Barr Fritcher EG, Levy MJ, Gores GJ. Advanced cytologic techniques for the detection of malignant pancreatobiliary strictures. Gastroenterology. 2006 Oct; 131 (4):1064-72 Epub 2006 Aug 16
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  134. Sinicrope FA, Rego RL, Halling KC, Foster N, Sargent DJ, La Plant B, French AJ, Laurie JA, Goldberg RM, Thibodeau SN, Witzig TE. Prognostic impact of microsatellite instability and DNA ploidy in human colon carcinoma patients. Gastroenterology. 2006 Sep; 131 (3):729-37
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  135. Halling KC, Rickman OB, Kipp BR, Harwood AR, Doerr CH, Jett JR. A comparison of cytology and fluorescence in situ hybridization for the detection of lung cancer in bronchoscopic specimens. Chest. 2006 Sep; 130 (3):694-701
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  136. Kipp BR, Campion MB, Coffman E, Smith A, Tomisek JD, Browne GG, Panella JR, Desai R, Harwood AR, Halling KC. An evaluation of ThinPrep UroCyte filters for the preparation of slides for fluorescence in situ hybridization. Diagn Cytopathol. 2006 Jul; 34 (7):479-84
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  137. Sinicrope FA, Rego RL, Halling KC, Foster NR, Sargent DJ, La Plant B, French AJ, Allegra CJ, Laurie JA, Goldberg RM, Witzig TE, Thibodeau SN. Thymidylate synthase expression in colon carcinomas with microsatellite instability. Clin Cancer Res. 2006 May 1; 12 (9):2738-44
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  138. Brankley SM, Wang KK, Harwood AR, Miller DV, Legator MS, Lutzke LS, Kipp BR, Morrison LE, Halling KC. The development of a fluorescence in situ hybridization assay for the detection of dysplasia and adenocarcinoma in Barrett's esophagus. J Mol Diagn. 2006 May; 8 (2):260-7
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  139. Kipp BR, Sebo TJ, Griffin MD, Ihrke JM, Halling KC. Analysis of polyomavirus-infected renal transplant recipients' urine specimens: correlation of routine urine cytology, fluorescence in situ hybridization, and digital image analysis. Am J Clin Pathol. 2005 Dec; 124(6):854-61.
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  140. Kipp BR, Fritcher EG, del Rosario KM, Stevens CL, Sebo TJ, Halling KC. A systematic approach to identifying urothelial cells likely to be polysomic by fluorescence in situ hybridization. Anal Quant Cytol Histol. 2005 Dec; 27(6):317-22.
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  141. Lewis JT, Ketterling RP, Halling KC, Reynolds C, Jenkins RB, Visscher DW. Analysis of intratumoral heterogeneity and amplification status in breast carcinomas with equivocal (2+) HER-2 immunostaining. Am J Clin Pathol. 2005 Aug; 124 (2):273-81
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  142. Kipp BR, Karnes RJ, Brankley SM, Harwood AR, Pankratz VS, Sebo TJ, Blute MM, Lieber MM, Zincke H, Halling KC. Monitoring intravesical therapy for superficial bladder cancer using fluorescence in situ hybridization. J Urol. 2005 Feb; 173: (2)401-4.
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  143. Kipp BR, Stadheim LM, Halling SA, Pochron NL, Harmsen S, Nagorney DM, Sebo TJ, Therneau TM, Gores GJ, de Groen PC, Baron TH, Levy MJ, Halling KC, Roberts LR. A comparison of routine cytology and fluorescence in situ hybridization for the detection of malignant bile duct strictures. Am J Gastroenterol. 2004 Sep; 99(9):1675-81.
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  144. Wang L, Baudhuin LM, Boardman LA, Steenblock KJ, Petersen GM, Halling KC, French AJ, Johnson RA, Burgart LJ, Rabe K, Lindor NM, Thibodeau SN. MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps. Gastroenterology. 2004 Jul; 127 (1):9-16
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  145. Morice WG, Kimlinger T, Katzmann JA, Lust JA, Heimgartner PJ, Halling KC, Hanson CA. Flow cytometric assessment of TCR-V-beta expression in the evaluation of peripheral blood involvement by T-cell lymphoproliferative disorders - A comparison with conventional T-cell immunophenotyping and molecular genetic techniques. Am J Clin Pathol. 2004 Mar; 121(3):373-83.
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  146. DeRosa M, Dourisboure R, Morelli G, Graziano A, Gutierrez A, Thibodeau S, Halling K, Avila KC, Duraturo F, Podesta EJ, Isso P, Solano AR. First genotype characterization of Argentinean FAP patients: Identification of 14 novel APC mutations. Hum Mutat. 2004; 23:523-524.
  147. Grogg KL, Lohse CM, Pankratz VS, Halling KC, Smyrk TC. Lymphocyte-rich gastric cancer: associations with Epstein-Barr virus, microsatellite instability, histology, and survival. Mod Pathol. 2003 Jul; 16 (7):641-51
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  148. Halling KC. Vysis (R) UroVysion for the detection of urothelial carcinoma. Expert Review of Molecular Diagnostics. 2003 Jul; 3(4):507-19.
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  149. Sokolova IA, Bubendorf L, O'Hare A, Legator MS, Jacobson KKB, Grilli B, Dalquen P, Halling KC, Tamm M, Seelig SA, Morrison LE. A fluorescence in situ hybridization-based assay for improved detection of lung cancer cells in bronchial washing specimens. Cancer Cytopathology. 2002 Oct 25; 96(5):306-15.
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  150. Halling KC, King W, Sokolova IA, Karnes RJ, Meyer RG, Powell EL, Sebo TJ, Cheville JC, Clayton AC, Krajnik KL, Ebert TA, Nelson RE, Burkhardt HM, Ramakumar S, Stewart CS, Pankratz VS, Lieber MM, Blute ML, Zincke H, Seelig SA, Jenkins RB, O'Kane DJ. A comparison of BTA stat, hemoglobin dipstick, telomerase and Vysis UroVysion assays for the detection of urothelial carcinoma in urine. J Urol. 2002 May; 167 (5):2001-6
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  151. Kakar S, Burgart LJ, Charlton MR, Saito Y, Saito Y, Halling K, Thibodeau SN. Origin of adenocarcinoma in a transplanted liver determined by microsatellite analysis. Hum Pathol. 2002 Apr; 33 (4):435-6
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  152. Perez EA, Roche PC, Jenkins RB, Reynolds CA, Halling KC, Ingle JN, Wold LE. HER2 testing in patients with breast cancer: poor correlation between weak positivity by immunohistochemistry and gene amplification by fluorescence in situ hybridization. Mayo Clin Proc. 2002 Feb; 77 (2):148-54
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  153. Aubry MC, Halling KC, Myers JL, Tazelaar HD, Yang P, Yang P, Thibodeau SN. DNA mismatch repair genes hMLH1, hMSH2, and hMSH6 are not inactivated in bronchioloalveolar carcinomas of the lung. Cancer. 2001 Dec 1; 92 (11):2898-901
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  154. Cunningham JM, Kim CY, Christensen ER, Tester DJ, Parc Y, Burgart LJ, Halling KC, McDonnell SK, Schaid DJ, Walsh Vockley C, Kubly V, Nelson H, Michels VV, Thibodeau SN. The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas. Am J Hum Genet. 2001 Oct; 69 (4):780-90 Epub 2001 Aug 24
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  155. Halling KC, Roche PC. Immunohistochemical Analysis for hMLH1 and hMSH2 Expression in Colorectal Cancer. Methods Mol Med. 2001; 50:81-6.
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  156. Parc YR, Halling KC. Microsatellite instability testing. Methods Mol Med. 2001; 50:69-79.
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  157. Yang P, Cunningham JM, Halling KC, Lesnick TG, Burgart LJ, Wiegert EM, Christensen ER, Lindor NM, Katzmann JA, Thibodeau SN. Higher risk of mismatch repair-deficient colorectal cancer in alpha(1)-antitrypsin deficiency carriers and cigarette smokers. Mol Genet Metab. 2000 Dec; 71 (4):639-45
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  158. Halling KC, King W, Sokolova IA, Meyer RG, Burkhardt HM, Halling AC, Cheville JC, Sebo TJ, Ramakumar S, Stewart CS, Pankratz S, O'Kane DJ, Seelig SA, Lieber MM, Jenkins RB. A comparison of cytology and fluorescence in situ hybridization for the detection of urothelial carcinoma. J Urol. 2000 Nov; 164 (5):1768-75
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  159. Liu W, Dong X, Mai M, Seelan RS, Taniguchi K, Krishnadath KK, Halling KC, Cunningham JM, Boardman LA, Qian C, Christensen E, Schmidt SS, Roche PC, Smith DI, Thibodeau SN. Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling. Nat Genet. 2000 Oct; 26(2):146-7.
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  160. Sokolova IA, Halling KC, Jenkins RB, Burkhardt HM, Meyer RG, Seelig SA, King W. The development of a multitarget, multicolor fluorescence in situ hybridization assay for the detection of urothelial carcinoma in urine. J Mol Diagn. 2000 Aug; 2(3):116-23.
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  161. Parc YR, Halling KC, Wang L, Christensen ER, Cunningham JM, French AJ, Burgart LJ, Price-Troska TL, Roche PC, Thibodeau SN. HMSH6 alterations in patients with microsatellite instability-low colorectal cancer. Cancer Res. 2000 Apr 15; 60(8):2225-31.
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  162. Parc YR, Halling KC, Burgart LJ, McDonnell SK, Schaid DJ, Thibodeau SN, Halling AC. Microsatellite instability and hMLH1/hMSH2 expression in young endometrial carcinoma patients: associations with family history and histopathology. Int J Cancer. 2000 Apr 1; 86 (1):60-6
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  163. Parc YR, Halling KC. Micro-satellite instability testing. Methods in Molecular Medicine. 2000; 50:69-79.
  164. Halling KC, Roche PC. Immunohistochemical analysis for hMLH1 and hMSH2 expression in colorectal cancer. Methods in Molecular Medicine. 2000; 50:81-86.
  165. Halling KC, French AJ, McDonnell SK, Burgart LJ, Schaid DJ, Peterson BJ, Moon-Tasson L, Mahoney MR, Sargent DJ, O'Connell MJ, Witzig TE, Farr GH Jr, Goldberg RM, Thibodeau SN. Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers. J Natl Cancer Inst. 1999 Aug 4; 91 (15):1295-303
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  166. Halling KC, Harper J, Moskaluk CA, Thibodeau SN, Petroni GR, Yustein AS, Tosi P, Minacci C, Roviello F, Piva P, Hamilton SR, Jackson CE, Powell SM. Origin of microsatellite instability in gastric cancer. Am J Pathol. 1999 Jul; 155 (1):205-11
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  167. Halling KC, Lazzaro CR, Honchel R, Bufill JA, Powell SM, Arndt CA, Lindor NM. Hereditary desmoid disease in a family with a germline Alu I repeat mutation of the APC gene. Hum Hered. 1999 Mar; 49(2):97-102.
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  168. Hancock JC, Wells A, Halling KC, Tilashalski K, Conner MG, Johns C, Listinsky CM. Composite B-cell and T-cell lymphoma arising 24 years after nodular lymphocyte predominant Hodgkin's disease. Ann Diagn Pathol. 1999; 3(1):23-34.
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  169. Kanomata N, Eble JN, Halling KC. Microsatellite instability is uncommon in young patients with renal cell carcinoma. Cancer Genet Cytogenet. 1998; 101(2):123-27.
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  170. Gayther SA, Gorringe KL, Ramus SJ, Huntsman D, Roviello F, Grehan N, Machado JC, Pinto E, Seruca R, Halling KC, MacLeod P, Powell SM, Jackson CE, Ponder BA, Caldas C. Identification of germ-line E-cadherin mutations in gastric cancer families of European origin. Cancer Res. 1998; 58:4086-89.
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  171. Halling KC, Bufill JA, Cotter M, Artz SA, Carpenter AB, Schaid D, Hartman-Adams H, Chang HH, Boustany MM, Fithian L, Jhiang SM, Thibodeau SN. Age-Related Disease Penetrance in a Large Medullary Thyroid Cancer Family With a Codon 609 RET Gene Mutation. Mol Diagn. 1997 Dec; 2 (4):277-286
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  172. Warschaw KE, Eble JN, Hood AF, Wolverton SE, Halling KC. The Muir-Torre syndrome in a black patient with AIDS: histopathology and molecular genetic studies. J Cutan Pathol. 1997 Sep; 24(8):511-8.
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  173. Swanson DA, Rothenberg HJ, Boynton AL, Consigliere D, Halling KC, Oda H, Smith D. Future prognostic factors for renal cell carcinoma - workgroup #5. Cancer. 1997 Sep 1; 80(5):997-998.
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  174. Kochhar R, Halling KC, McDonnell S, McDonnell S, Schaid DJ, French AJ, O'Connell MJ, Nagorney DM, Thibodeau SN. Allelic imbalance and microsatellite instability in resected Duke's D colorectal cancer. Diagn Mol Pathol. 1997 Apr; 6 (2):78-84
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  175. Kanomata N, Eble JN, Halling KC. Nonrandom X chromosome inactivation in cystic nephroma demonstrates the neoplastic nature of these tumors. J Urol Pathol. 1997; 7:81-7.
  176. Thibodeau SN, French AJ, Roche PC, Cunningham JM, Tester DJ, Lindor NM, Moslein G, Baker SM, Liskay RM, Burgart LJ, Honchel R, Halling KC. Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes. Cancer Res. 1996 Nov 01; 56: (21)4836-40.
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  177. Moslein G, Tester DJ, Lindor NM, Honchel R, Cunningham JM, French AJ, Halling KC, Schwab M, Goretzki P, Thibodeau SN. Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer. Hum Mol Genet. 1996 Sep; 5 (9):1245-52
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  178. Halling KC, Scheithauer BW, Halling AC, Nascimento AG, Ziesmer SC, Roche PC, Wollan PC. p53 expression in neurofibroma and malignant peripheral nerve sheath tumor. An immunohistochemical study of sporadic and NF1-associated tumors. Am J Clin Pathol. 1996 Sep; 106 (3):282-8
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  179. Halling KC, Honchel R, Pittelkow MR, Thibodeau SN. Microsatellite instability in keratoacanthoma. Cancer. 1995 Nov 15; 76 (10):1765-71
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  180. Honchel R, Halling KC, Thibodeau SN. Genomic instability in neoplasia. Semin Cell Biol. 1995 Feb; 6 (1):45-52
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  181. Barksdale SK, Perniciaro C, Halling KC, Strickler JG. Granuloma annulare in patients with malignant lymphoma: clinicopathologic study of thirteen new cases. J Am Acad Dermatol. 1994 Jul; 31 (1):42-8
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  182. Honchel R, Halling KC, Schaid DJ, Pittelkow M, Thibodeau SN. Microsatellite instability in Muir-Torre syndrome. Cancer Res. 1994 Mar 1; 54(5):1159-63.
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  183. Cliby W, Ritland S, Hartmann L, Dodson M, Halling KC, Keeney G, Podratz KC, Jenkins RB. Human epithelial ovarian cancer allelotype. Cancer Res. 1993 May 15; 53 (10 Suppl):2393-8
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  184. Ladin BF, Murray EE, Halling AC, Halling KC, Tilakaratne N, Long GL, Houston LL, Weaver RF. Characterization of a cDNA encoding ricin E, a hybrid ricin-ricinus communis agglutinin gene from the castor plant recinus communis. Plant Mol Biol. 1987; 9:287-295.
  185. Halling KC, Halling AC, Murray EE, Ladin BF, Houston LL, Weaver RF. Genomic cloning and characterization of a ricin gene from Ricinus communis. Nucleic Acids Res. 1985 Nov 25; 13(22):8019-33.
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