المنشورات طباعة Cook DJ, Decker PA, Hardcastle JJ, Kollmeyer TM, Smoley SA, Isaacson MD, Gandham M, Dasari S, Abdullaev Z, Aldape K, Quezado M, Cimino PJ, Pratt DW, Giannini C, Nguyen A, Raghunathan A, Trejo-Lopez JA, Vaubel RA, Vizcaino MA, Mendoza CJZ, Al Kateb H, Jenkins RB, Ida CM. EGFR transcript variants: Potential diagnostic biomarker for glioblastoma, IDH-wildtype? J Neuropathol Exp Neurol. 2025 Apr 25 [Epub ahead of print] View PubMed Xue Z, Mladek AC, Rathi S, Jain S, Vaubel RA, Odukoya LA, Garcia DA, Liu L, Bakken KK, Carlson BL, Ott LL, Burgenske DM, Hu Z, Dragojevic S, Decker PA, Kosel ML, Breen WG, Gupta SK, Eckel-Passow JE, Elmquist WF, Zhong W, Sarkaria JN. The novel brain penetrant ATM inhibitor WSD0628 provides robust radiosensitization of brain tumor patient derived xenografts. Neuro Oncol. 2025 Apr 15 [Epub ahead of print] View PubMed Cook DJ, Trejo-Lopez JA, Pitel BA, Saha N, Koganti T, Hardcastle J, Smoley S, Isaacson M, Gandham M, Sivasankaran G, Dasari S, Fung KM, Powell SZ, Trivedi D, Abdullaev Z, Aldape K, Quezado M, Pratt D, Cimino PJ, Edgar MA, Vaubel RA, Raghunathan A, Giannini C, Jenkins RB, Ida CM. Expanding the spectrum of TERT promoter mutations in CNS tumors: A case series of non-canonical mutations. J Neuropathol Exp Neurol. 2025 Mar 19 [Epub ahead of print] View PubMed Garcia DA, Rathi S, Connors MA, Grams M, Vaubel RA, Bakken KK, Ott LL, Carlson BL, Hu Z, Decker PA, Eckel-Passow JE, Burgenske DM, Zhong W, Trzasko JD, Herman MG, Elmquist WF, Remmes NB, Sarkaria JN. Modeling the Acute Mucosal Toxicity of Fractionated Radiotherapy Combined with the ATM Inhibitor WSD0628. Mol Cancer Ther. 2025 Feb 4; 24 (2):299-309 View PubMed Vizcaino MA, Giannini C, Vaubel RA, Nguyen AT, Trejo-Lopez JA, Raghunathan A, Jenkins SM, Jenkins RB, Zepeda Mendoza CJ. Comparing loss of p16 and MTAP expression in detecting CDKN2A homozygous deletion in pleomorphic xanthoastrocytoma. J Neuropathol Exp Neurol. 2024 Dec 1; 83 (12):1003-1009 View PubMed Odukoya LA, Ida CM, Eckel-Passow JE, Kollmeyer TM, Vaubel R, Lachance DH, Fonkem E, Badmos KB, Bankole OB, Llewellyn H, Kitange GJ, Aldape K, Daramola AO, Anunobi CC, Jenkins RB. Histopathologic and molecular profile of gliomas diagnosed in Lagos, Nigeria. Neurooncol Pract. 2024 Dec; 11 (6):753-762 Epub 2024 June 22 View PubMed Jain S, Griffith JI, Porath KA, Rathi S, Le J, Pasa TI, Decker PA, Gupta SK, Hu Z, Carlson BL, Bakken K, Burgenske DM, Feldsien TM, Lefebvre DR, Vaubel RA, Eckel-Passow JE, Reilly EB, Elmquist WF, Sarkaria JN. Bystander Effects, Pharmacokinetics, and Linker-Payload Stability of EGFR-Targeting Antibody-Drug Conjugates Losatuxizumab Vedotin and Depatux-M in Glioblastoma Models. Clin Cancer Res. 2024 Aug 1; 30 (15):3287-3297 View PubMed Onubogu U, Gatenbee CD, Prabhakaran S, Wolfe KL, Oakes B, Salatino R, Vaubel R, Szentirmai O, Anderson AR, Janiszewska M. Spatial analysis of recurrent glioblastoma reveals perivascular niche organization. JCI Insight. 2024 May 23; 9 (12) View PubMed Vizcaino MA, Giannini C, Lalich D, Nael A, Jenkins RB, Tran Q, Orr BA, Abdullaev Z, Aldape K, Vaubel RA. Ganglioglioma with anaplastic/high-grade transformation: Histopathologic, molecular, and epigenetic characterization of 3 cases. J Neuropathol Exp Neurol. 2024 May 22; 83 (6):416-424 View PubMed Chen J, Laverty DJ, Talele S, Bale A, Carlson BL, Porath KA, Bakken KK, Burgenske DM, Decker PA, Vaubel RA, Eckel-Passow JE, Bhargava R, Lou Z, Hamerlik P, Harley B, Elmquist WF, Nagel ZD, Gupta SK, Sarkaria JN. Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization. Sci Transl Med. 2024 Feb 14; 16 (734):eadj5962 View PubMed Zhang W, Vaubel RA, Oh JH, Mladek AC, Talele S, Zhang W, Waller KL, Burgenske DM, Sarkaria JN, Elmquist WF. Delivery versus Potency in Treating Brain Tumors: BI-907828, a MDM2-p53 Antagonist with Limited BBB Penetration but Significant In Vivo Efficacy in Glioblastoma. Mol Cancer Ther. 2024 Jan 3; 23 (1):47-55 View PubMed Elhalaby RE, Kavran CA, Vaubel RA, Vizcaino Villalobos MA. Left dural-based mass in a 62-year-old female. Brain Pathol. 2023 Jul; 33(4):e13145. Epub 2023 Feb 06. View PubMed Riviere-Cazaux C, Carlstrom LP, Rajani K, Munoz-Casabella A, Rahman M, Gharibi-Loron A, Brown DA, Miller KJ, White JJ, Himes BT, Jusue-Torres I, Ikram S, Ransom SC, Hirte R, Oh JH, Elmquist WF, Sarkaria JN, Vaubel RA, Rodriguez M, Warrington AE, Kizilbash SH, Burns TC. Blood-brain barrier disruption defines the extracellular metabolome of live human high-grade gliomas. Commun Biol. 2023 Jun 20; 6 (1):653 Epub 2023 June 20 View PubMed Guerin JB, Kaufmann TJ, Eckel LJ, Morris JM, Vaubel RA, Giannini C, Johnson DR. A Radiologist's Guide to the 2021 WHO Central Nervous System Tumor Classification: Part 2-Newly Described and Revised Tumor Types. Radiology. 2023 Jun; 307 (5):e221885 Epub 2023 May 16 View PubMed Yagnik KJ, Vakharia K, Vaubel RA, Vizcaino MA, Benson JC, Daniels DJ, Link MJ, Van Gompel JJ. Surgical Experience and Management of Intracranial Neurenteric Cysts: Single-Center Experience and Review of the Literature. J Neurol Surg B Skull Base. 2023 Jun; 84 (3):272-280 Epub 2022 Apr 19 View PubMed Vaubel RA, Kumar R, Weiskittel TM, Jenkins S, Dasari S, Uhm JH, Lachance DH, Brown PD, Van Gompel JJ, Jenkins RB, Kipp BR, Sukov WR, Giannini C, Johnson DR, Raghunathan A. Genomic markers of recurrence risk in atypical meningioma following gross total resection. Neurooncol Adv. 2023 Jan-Dec; 5 (1):vdad004 Epub 2023 Jan 10 View PubMed Johnson DR, Giannini C, Vaubel RA, Morris JM, Eckel LJ, Kaufmann TJ, Guerin JB. A Radiologist's Guide to the 2021 WHO Central Nervous System Tumor Classification: Part I-Key Concepts and the Spectrum of Diffuse Gliomas. Radiology. 2022 Sep; 304 (3):494-508 Epub 2022 July 26 View PubMed Burgenske DM, Talele S, Pokorny JL, Mladek AC, Bakken KK, Carlson BL, Schroeder MA, He L, Hu Z, Gampa G, Kosel ML, Decker PA, Kitange GJ, Schmitt-Hoffmann A, Bachmann F, Vaubel RA, Eckel-Passow JE, Giannini C, McSheehy P, Lane HA, Elmquist WF, Sarkaria JN. Preclinical modeling in glioblastoma patient-derived xenograft (GBM PDX) xenografts to guide clinical development of lisavanbulin-a novel tumor checkpoint controller targeting microtubules. Neuro Oncol. 2022 Mar 12; 24 (3):384-395 View PubMed Porath KA, Regan MS, Griffith JI, Jain S, Stopka SA, Burgenske DM, Bakken KK, Carlson BL, Decker PA, Vaubel RA, Dragojevic S, Mladek AC, Connors MA, Hu Z, He L, Kitange GJ, Gupta SK, Feldsien TM, Lefebvre DR, Agar NYR, Eckel-Passow JE, Reilly EB, Elmquist WF, Sarkaria JN. Convection enhanced delivery of EGFR targeting antibody-drug conjugates Serclutamab talirine and Depatux-M in glioblastoma patient-derived xenografts. Neurooncol Adv. 2022 Jan-Dec; 4 (1):vdac130 Epub 2022 Aug 24 View PubMed Marin BM, Porath KA, Jain S, Kim M, Conage-Pough JE, Oh JH, Miller CL, Talele S, Kitange GJ, Tian S, Burgenske DM, Mladek AC, Gupta SK, Decker PA, McMinn MH, Stopka SA, Regan MS, He L, Carlson BL, Bakken K, Burns TC, Parney IF, Giannini C, Agar NYR, Eckel-Passow JE, Cochran JR, Elmquist WF, Vaubel RA, White FM, Sarkaria JN. Heterogeneous delivery across the blood-brain barrier limits the efficacy of an EGFR-targeting antibody drug conjugate in glioblastoma. Neuro Oncol. 2021 Dec 1; 23 (12):2042-2053 View PubMed Vizcaino MA, Giannini C, Chang HT, Kipp BR, Fritchie K, Vaubel R. Intracranial angiomatoid fibrous histiocytoma with rhabdoid features: a mimic of rhabdoid meningioma. Brain Tumor Pathol. 2021 Apr; 38(2):138-144. Epub 2021 Jan 12. View PubMed Vaubel R, Zschernack V, Tran QT, Jenkins S, Caron A, Milosevic D, Smadbeck J, Vasmatzis G, Kandels D, Gnekow A, Kramm C, Jenkins R, Kipp BR, Rodriguez FJ, Orr BA, Pietsch T, Giannini C. Biology and grading of pleomorphic xanthoastrocytoma-what have we learned about it? Brain Pathol. 2021 Jan; 31 (1):20-32 Epub 2020 Aug 04 View PubMed Swanson A, Giannini C, Link M, Van Gompel J, Wald J, McPhail E, Theis J, Vaubel R. Trigeminal Amyloidoma: A Report of Two Cases and Review of the Literature. J Neurol Surg B Skull Base. 2020 Dec; 81 (6):620-626 Epub 2019 July 30 View PubMed Zepeda-Mendoza CJ, Vaubel RA, Zarei S, Ida CM, Matthews M, Acree S, Raghunathan A, Giannini C, Jenkins RB. Concomitant 1p/19q co-deletion and IDH1/2, ATRX, and TP53 mutations within a single clone of "dual-genotype" IDH-mutant infiltrating gliomas. Acta Neuropathol. 2020 Jun; 139 (6):1105-1107 Epub 2020 Mar 13 View PubMed Vaubel RA, Tian S, Remonde D, Schroeder MA, Mladek AC, Kitange GJ, Caron A, Kollmeyer TM, Grove R, Peng S, Carlson BL, Ma DJ, Sarkar G, Evers L, Decker PA, Yan H, Dhruv HD, Berens ME, Wang Q, Marin BM, Klee EW, Califano A, LaChance DH, Eckel-Passow JE, Verhaak RG, Sulman EP, Burns TC, Meyer FB, O'Neill BP, Tran NL, Giannini C, Jenkins RB, Parney IF, Sarkaria JN. Genomic and Phenotypic Characterization of a Broad Panel of Patient-Derived Xenografts Reflects the Diversity of Glioblastoma. Clin Cancer Res. 2020 Mar 1; 26 (5):1094-1104 Epub 2019 Dec 18 View PubMed Burgenske DM, Yang J, Decker PA, Kollmeyer TM, Kosel ML, Mladek AC, Caron AA, Vaubel RA, Gupta SK, Kitange GJ, Sicotte H, Youland RS, Remonde D, Voss JS, Fritcher EGB, Kolsky KL, Ida CM, Meyer FB, Lachance DH, Parney IJ, Kipp BR, Giannini C, Sulman EP, Jenkins RB, Eckel-Passow JE, Sarkaria JN. Molecular profiling of long-term IDH-wildtype glioblastoma survivors. Neuro Oncol. 2019 Nov 4; 21 (11):1458-1469 View PubMed Blackburn PR, Chacon-Camacho OF, Ortiz-Gonzalez XR, Reyes M, Lopez-Uriarte GA, Zarei S, Bhoj EJ, Perez-Solorzano S, Vaubel RA, Murphree MI, Nava J, Cortes-Gonzalez V, Parisi JE, Villanueva-Mendoza C, Tirado-Torres IG, Li D, Klee EW, Pichurin PN, Zenteno JC. Extension of the mutational and clinical spectrum of SOX2 related disorders: Description of six new cases and a novel association with suprasellar teratoma. Am J Med Genet A. 2018 Dec; 176 (12):2710-2719 Epub 2018 Nov 18 View PubMed Kim M, Ma DJ, Calligaris D, Zhang S, Feathers RW, Vaubel RA, Meaux I, Mladek AC, Parrish KE, Jin F, Barriere C, Debussche L, Watters J, Tian S, Decker PA, Eckel-Passow JE, Kitange GJ, Johnson AJ, Parney IF, Anastasiadis PZ, Agar NYR, Elmquist WF, Sarkaria JN. Efficacy of the MDM2 Inhibitor SAR405838 in Glioblastoma Is Limited by Poor Distribution Across the Blood-Brain Barrier. Mol Cancer Ther. 2018 Sep; 17 (9):1893-1901 Epub 2018 July 03 View PubMed Vaubel RA, Ross Reichard R. A 56-year-old woman with blindness and mental status changes. Brain Pathol. 2018 Jul; 28 (4):583-584 View PubMed Swanson AA, Giannini C, Folpe AL, Van Dyke DL, Amrami KK, Michalak WA, Vaubel RA. Low-grade fibromyxoid sarcoma arising within the median nerve. Neuropathology. 2018 Jun; 38 (3):309-314 Epub 2018 Jan 03 View PubMed Vaubel RA, Caron AA, Yamada S, Decker PA, Eckel Passow JE, Rodriguez FJ, Nageswara Rao AA, Lachance D, Parney I, Jenkins R, Giannini C. Recurrent copy number alterations in low-grade and anaplastic pleomorphic xanthoastrocytoma with and without BRAF V600E mutation. Brain Pathol. 2018 Mar; 28(2):172-182. Epub 2017 Apr 02. View PubMed Vaubel RA, Kollmeyer TM, Caron AA, Barr Fritcher EG, Voss JS, Liang H, Jenkins RB, Giannini C, Kipp BR. Synchronous gemistocytic astrocytoma IDH-mutant and oligodendroglioma IDH-mutant and 1p/19q-codeleted in a patient with CCDC26 polymorphism. Acta Neuropathol. 2017 Aug; 134(2):317-319. Epub 2017 May 26. View PubMed Shankar GM, Abedalthagafi M, Vaubel RA, Merrill PH, Nayyar N, Gill CM, Brewster R, Bi WL, Agarwalla PK, Thorner AR, Reardon DA, Al-Mefty O, Wen PY, Alexander BM, van Hummelen P, Batchelor TT, Ligon KL, Ligon AH, Meyerson M, Dunn IF, Beroukhim R, Louis DN, Perry A, Carter SL, Giannini C, Curry WT Jr, Cahill DP, Barker FG 2nd, Brastianos PK, Santagata S. Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas. Neuro Oncol. 2017 Apr 1; 19 (4):535-545 View PubMed Vaubel RA, Raghunathan A, Erickson LA. Parkinson Disease. Mayo Clin Proc. 2016 Nov; 91 (11):e155-e156 View PubMed Elsherif MA, Wenger DE, Vaubel RA, Spinner RJ. Nerve-Adherent Giant Cell Tumors of Tendon Sheath: A New Presentation. World Neurosurg. 2016 Aug; 92:583.e19-583.e24 Epub 2016 May 29 View PubMed Vaubel R, Jones A, Salomão D. Retroperitoneal Metastasis of an Anaplastic Oligodendroglioma Diagnosed by Fine Needle Aspiration Biopsy (FNAB) Sixteen Years after Primary Resection ASCP Case Reports: Cytology. 2016. Vaubel RA, Chang HT, Fritchie K, Abell Aleff PC, Jentoft ME. Epithelioid Schwannoma of a Spinal Nerve Root. Can J Neurol Sci. 2016 May; 43 (3):430-3 Epub 2016 Jan 07 View PubMed Vaubel RA, Chen SG, Raleigh DR, Link MJ, Chicoine MR, Barani I, Jenkins SM, Aleff PA, Rodriguez FJ, Burger PC, Dahiya S, Perry A, Giannini C. Meningiomas With Rhabdoid Features Lacking Other Histologic Features of Malignancy: A Study of 44 Cases and Review of the Literature. J Neuropathol Exp Neurol. 2016 Jan; 75 (1):44-52 Epub 2015 Dec 07 View PubMed Vaubel RA, Raghunathan A, Erickson LA. Parkinson disease Mayo Clinic Proceedings. 2016; 91(11):e155-6. Epub 1900 Jan 01. Reichard R, Vaubel R. Investigation of Deaths in Seizure Patients. Acad Forensic Pathol. 2014 4; (3):331-337. Vaubel RA, Isaya G. Iron-sulfur cluster synthesis, iron homeostasis and oxidative stress in Friedreich ataxia. Mol Cell Neurosci. 2013 Jul; 55:50-61 Epub 2012 Aug 11 View PubMed Vaubel RA, Rustin P, Isaya G. Mutations in the dimer interface of dihydrolipoamide dehydrogenase promote site-specific oxidative damages in yeast and human cells. J Biol Chem. 2011 Nov 18; 286 (46):40232-45 Epub 2011 Sept 19 View PubMed Olivotto I, Girolami F, Ackerman MJ, Nistri S, Bos JM, Zachara E, Ommen SR, Theis JL, Vaubel RA, Re F, Armentano C, Poggesi C, Torricelli F, Cecchi F. Myofilament protein gene mutation screening and outcome of patients with hypertrophic cardiomyopathy. Mayo Clin Proc. 2008 Jun; 83(6):630-8. View PubMed PST-20513809 الصفحة الرئيسية المنشورات