المنشورات طباعة Croatt AJ, Singh RD, Grande JP, Ackerman AW, Gurley SB, Barry MA, Juncos LA, Nath KA. ACE2 deficiency protects against heme protein-induced acute kidney injury. Am J Physiol Renal Physiol. 2025 May 1; 328 (5):F676-F683 Epub 2025 Mar 25 View PubMed Nath KA, Juncos LA, Singh RD, Grande JP, Croatt AJ, Ackerman AW, Kanamori KS, Adams CM, Tchkonia T, Kirkland JL, Katusic ZS. The Occurrence of Senescence in the Arteriovenous Fistula in the Rat. Kidney360. 2025 Jan 1; 6 (1):27-37 Epub 2024 Oct 17 View PubMed Denic A, Rule AD, Park WD, Smith BH, Mejia MV, Kukla A, Grande JP, Stegall MD. IFTA Foci Density: An Unrecognized Highly Prognostic Measurement of Fibrosis in Kidney Transplant Biopsies. Kidney360 2024 Sep 1; 5 (9):1341-1349 Epub 2024 July 18 View PubMed Denic A, Buglioni A, Turkevi-Nagy S, Mejia MV, Smith BH, Park WD, Subramani R, Kukla A, Diwan TS, Grande JP, Stegall MD. Mesangial Expansion by Morphometry at 5 y After Kidney Transplantation: Incidence, Risk Factors, and Association With Graft Loss. Transplant Direct. 2024 Jul; 10 (7):e1652 Epub 2024 June 13 View PubMed Nath KA, Singh RD, Croatt AJ, Ackerman AW, Grande JP, O'Brien DR, Garovic VD, Adams CM, Tchkonia T, Kirkland JL. Induction of p16Ink4a Gene Expression in Heme Protein-Induced AKI and by Heme: Pathophysiologic Implications. Kidney360. 2024 Apr 1; 5 (4):501-514 Epub 2024 Feb 21 View PubMed Grande J, Jones TL, Sun Z, Chanana P, Jaiswal I, Leontovich A, Carapanceanu N, Carapanceanu V, Saadalla A, Osman A, Famuyide AO, Daftary GS, Khan Z, Khazaie K. Corrigendum to "Host immunity and KLF 11 deficiency together promote fibrosis in a mouse model of endometriosis" [BBA - Mol. Basis of Dis. 1869 (2023) 166784]. Biochim Biophys Acta Mol Basis Dis. 2024 Mar; 1870 (3):166923 Epub 2023 Nov 08 View PubMed Vasconcelos L, Kijanka P, Grande JP, Oliveira R, Amador C, Aristizabal S, Sanger NM, Rule AD, Atwell TD, Urban MW. Kidney cortex shear wave motion simulations based on segmented biopsy histology. Comput Methods Programs Biomed. 2024 Mar; 245:108035 Epub 2024 Jan 15 View PubMed Liang Y, Ozdogan E, Hansen MJ, Tang H, Saadiq I, Jordan KL, Krier JD, Gandhi DB, Grande JP, Lerman LO, Taner T. Human liver derived mesenchymal stromal cells ameliorate murine ischemia-induced inflammation through macrophage polarization. Front Immunol. 2024; 15:1448092 Epub 2024 July 22 View PubMed Grande J, Jones TL, Sun Z, Chanana P, Jaiswal I, Leontovich A, Carapanceanu N, Carapanceanu V, Saadalla A, Osman A, Famuyide AO, Daftary GS, Khan Z, Khazaie K. Host immunity and KLF 11 deficiency together promote fibrosis in a mouse model of endometriosis. Biochim Biophys Acta Mol Basis Dis. 2023 Oct; 1869 (7):166784 Epub 2023 June 13 View PubMed Sethi A, Grande J, Specks U, Fervenza FC. Proteomic profile of uninvolved versus crescentic glomeruli in MPO-ANCA-associated vasculitis. Clin Kidney J. 2023 Jul; 16 (7):1180-1182 Epub 2023 Feb 16 View PubMed Denic A, Bogojevic M, Subramani R, Park WD, Smith BH, Alexander MP, Grande JP, Kukla A, Schinstock CA, Bentall AJ, Rule AD, Stegall MD. Changes in Glomerular Volume, Sclerosis, and Ischemia at 5 Years after Kidney Transplantation: Incidence and Correlation with Late Graft Failure. J Am Soc Nephrol. 2023 Feb 1; 34 (2):346-358 Epub 2022 Nov 17 View PubMed Smith B, Grande J, Ryan M, Smith M, Denic A, Hermsen M, Park W, Kremers W, Stegall M. Automated scoring of total inflammation in renal allograft biopsies. Clin Transplant. 2023 Jan; 37 (1):e14837 Epub 2022 Nov 30 View PubMed Singh RD, Croatt AJ, Ackerman AW, Grande JP, Trushina E, Salisbury JL, Christensen TA, Adams CM, Tchkonia T, Kirkland JL, Nath KA. Prominent Mitochondrial Injury as an Early Event in Heme Protein-Induced Acute Kidney Injury. Kidney360. 2022 Oct 27; 3 (10):1672-1682 Epub 2022 Aug 15 View PubMed Rozenova KA, Lehman JS, Grande JP, Fine AL, Wieland CN. Utilization of skin biopsy for diagnosis in a case of Lafora disease. J Cutan Pathol. 2022 Oct; 49 (10):885-888 Epub 2022 July 06 View PubMed Klomjit N, Zhu XY, Eirin A, Pawar AS, Conley SM, Puranik AS, Ferguson CM, Kim SR, Tang H, Jordan KL, Saadiq IM, Lerman A, Grande JP, Textor SC, Lerman LO. Microvascular remodeling and altered angiogenic signaling in human kidneys distal to occlusive atherosclerotic renal artery stenosis. Nephrol Dial Transplant. 2022 Sep 22; 37 (10):1844-1856 View PubMed Nath KA, Singh RD, Croatt AJ, Ackerman AW, Grande JP, Khazaie K, Chen YE, Zhang J. KLF11 Is a Novel Endogenous Protectant against Renal Ischemia-Reperfusion Injury. Kidney360. 2022 Aug 25; 3 (8):1417-1422 Epub 2022 May 06 View PubMed Singh RD, Barry MA, Croatt AJ, Ackerman AW, Grande JP, Diaz RM, Vile RG, Agarwal A, Nath KA. The spike protein of SARS-CoV-2 induces heme oxygenase-1: Pathophysiologic implications. Biochim Biophys Acta Mol Basis Dis. 2022 Mar 1; 1868 (3):166322 Epub 2021 Dec 14 View PubMed Matas AJ, Helgeson E, Fieberg A, Leduc R, Gaston RS, Kasiske BL, Rush D, Hunsicker L, Cosio F, Grande JP, Cecka JM, Connett J, Mannon RB. Risk Prediction for Delayed Allograft Function: Analysis of the Deterioration of Kidney Allograft Function (DeKAF) Study Data. Transplantation. 2022 Feb 1; 106 (2):358-368 View PubMed De Lorenzo SB, Vrieze AM, Johnson RA, Lien KR, Nath KA, Garovic VD, Khazaie K, Grande JP. KLF11 deficiency enhances chemokine generation and fibrosis in murine unilateral ureteral obstruction. PLoS One. 2022; 17 (4):e0266454 Epub 2022 Apr 12 View PubMed Grande JP, Helgeson ES, Matas AJ. Correlation of Glomerular Size With Donor-Recipient Factors and With Response to Injury. Transplantation. 2021 Nov 1; 105 (11):2451-2460 View PubMed Alexander MP, Mangalaparthi KK, Madugundu AK, Moyer AM, Adam BA, Mengel M, Singh S, Herrmann SM, Rule AD, Cheek EH, Herrera Hernandez LP, Graham RP, Aleksandar D, Aubry MC, Roden AC, Hagen CE, Quinton RA, Bois MC, Lin PT, Maleszewski JJ, Cornell LD, Sethi S, Pavelko KD, Charlesworth J, Narasimhan R, Larsen CP, Rizza SA, Nasr SH, Grande JP, McKee TD, Badley AD, Pandey A, Taner T. Acute Kidney Injury in Severe COVID-19 Has Similarities to Sepsis-Associated Kidney Injury: A Multi-Omics Study. Mayo Clin Proc. 2021 Oct; 96 (10):2561-2575 Epub 2021 July 15 View PubMed Suvakov S, Ghamrawi R, Cubro H, Tu H, White WM, Tobah YSB, Milic NM, Grande JP, Cunningham JM, Chebib FT, Prata LGPL, Zhu Y, Tchkonia T, Kirkland JL, Nath KA, Milosavljevic A, Garovic VD. Epigenetic and senescence markers indicate an accelerated ageing-like state in women with preeclamptic pregnancies. EBioMedicine. 2021 Aug; 70:103536 Epub 2021 Aug 11 View PubMed Nath KA, Singh RD, Grande JP, Garovic VD, Croatt AJ, Ackerman AW, Barry MA, Agarwal A. Expression of ACE2 in the Intact and Acutely Injured Kidney. Kidney360. 2021 Jul 29; 2 (7):1095-1106 Epub 2021 May 18 View PubMed Helgeson ES, Mannon R, Grande J, Gaston RS, Cecka MJ, Kasiske BL, Rush D, Gourishankar S, Cosio F, Hunsicker L, Connett J, Matas AJ. i-IFTA and chronic active T cell-mediated rejection: A tale of 2 (DeKAF) cohorts. Am J Transplant. 2021 May; 21 (5):1866-1877 Epub 2020 Nov 08 View PubMed Ravindran A, Casal Moura M, Fervenza FC, Nasr SH, Alexander MP, Fidler ME, Herrera Hernandez LP, Zhang P, Grande JP, Cornell LD, Gross LA, Negron V, Jenson GE, Madden BJ, Charlesworth MC, Sethi S. In Patients with Membranous Lupus Nephritis, Exostosin-Positivity and Exostosin-Negativity Represent Two Different Phenotypes. J Am Soc Nephrol. 2021 Mar; 32 (3):695-706 Epub 2021 Jan 21 View PubMed Cubro H, Nath KA, Suvakov S, Garcia-Valencia O, Parashuram S, White WM, Weissgerber TL, Nath MC, Milic NM, Sontag F, d'Uscio LV, Zhu Y, Kirkland JL, Tchkonia T, Alexander MP, Quinton RA, Katusic ZS, Grande JP, Garovic VD. Mechanisms of vascular dysfunction in the interleukin-10-deficient murine model of preeclampsia indicate nitric oxide dysregulation. Kidney Int. 2021 Mar; 99 (3):646-656 Epub 2020 Nov 02 View PubMed El Ters M, Bobart SA, Cornell LD, Leung N, Bentall A, Sethi S, Fidler M, Grande J, Hernandez LH, Cosio FG, Zand L, Amer H, Fervenza FC, Nasr SH, Alexander MP. Recurrence of DNAJB9-Positive Fibrillary Glomerulonephritis After Kidney Transplantation: A Case Series. Am J Kidney Dis. 2020 Oct; 76 (4):500-510 Epub 2020 May 12 View PubMed Matas AJ, Helgeson ES, Gaston R, Cosio F, Mannon R, Kasiske BL, Hunsicker L, Gourishankar S, Rush D, Michael Cecka J, Connett J, Grande JP. Inflammation in areas of fibrosis: The DeKAF prospective cohort. Am J Transplant. 2020 Sep; 20 (9):2509-2521 Epub 2020 Apr 15 View PubMed Said SM, Leung N, Alexander MP, Cornell LD, Fidler ME, Grande JP, Herrera LH, Sethi S, Zhang P, Nasr SH. DNAJB9-positive monotypic fibrillary glomerulonephritis is not associated with monoclonal gammopathy in the vast majority of patients. Kidney Int. 2020 Aug; 98 (2):498-504 Epub 2020 Mar 28 View PubMed Bobart SA, Owoyemi I, Grande J, Leung N, Herrmann SM. Immune Check Point Inhibitor-Associated Endothelialitis. Kidney Int Rep. 2020 Aug; 5 (8):1371-1374 Epub 2020 June 03 View PubMed Garle A, Miller A, Sarrafian T, Tonne J, Ikeda Y, Grande JP, Wigle D, Yaszemski M, Kudva Y. Development of nanoporous polyurethane hydrogel membranes for cell encapsulation Regenerative Engineering and Translational Medicine. 2020 Jun; 6(2):217-27. Nath KA, Grande JP, Belcher JD, Garovic VD, Croatt AJ, Hillestad ML, Barry MA, Nath MC, Regan RF, Vercellotti GM. Antithrombotic effects of heme-degrading and heme-binding proteins. Am J Physiol Heart Circ Physiol. 2020 Mar 1; 318 (3):H671-H681 Epub 2020 Jan 31 View PubMed Buglioni A, Fidler ME, Alexander MP, Sethi S, Nasr SH, Hernandez LPH, Grande JP, Cosio FG, Cornell LD. De novo pauci-immune glomerulonephritis in renal allografts. Mod Pathol. 2020 Mar; 33 (3):440-447 Epub 2019 Sept 02 View PubMed Gonzalez Suarez ML, Zhang P, Nasr SH, Sathick IJ, Kittanamongkolchai W, Kurtin PJ, Alexander MP, Cornell LD, Fidler ME, Grande JP, Herrera Hernandez LP, Said SM, Sethi S, Dispenzieri A, Gertz MA, Leung N. The sensitivity and specificity of the routine kidney biopsy immunofluorescence panel are inferior to diagnosing renal immunoglobulin-derived amyloidosis by mass spectrometry. Kidney Int. 2019 Oct; 96 (4):1005-1009 Epub 2019 June 25 View PubMed Suvakov S, Cubro H, White WM, Butler Tobah YS, Weissgerber TL, Jordan KL, Zhu XY, Woollard JR, Chebib FT, Milic NM, Grande JP, Xu M, Tchkonia T, Kirkland JL, Lerman LO, Garovic VD. Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia. Biol Sex Differ. 2019 Sep 14; 10 (1):49 Epub 2019 Sept 14 View PubMed Nath KA, Garovic VD, Grande JP, Croatt AJ, Ackerman AW, Farrugia G, Katusic ZS, Belcher JD, Vercellotti GM. Heme oxygenase-2 protects against ischemic acute kidney injury: influence of age and sex. Am J Physiol Renal Physiol. 2019 Sep 1; 317 (3):F695-F704 Epub 2019 June 19 View PubMed Raymond MR, Grande JP. A practical guide to test blueprinting. Med Teach. 2019 Aug; 41 (8):854-861 Epub 2019 Apr 24 View PubMed Oh S, Shin S, Song H, Grande JP, Janknecht R. Relationship between ETS Transcription Factor ETV1 and TGF-beta-regulated SMAD Proteins in Prostate Cancer. Sci Rep. 2019 Jun 3; 9 (1):8186 Epub 2019 June 03 View PubMed Palmer AK, Xu M, Zhu Y, Pirtskhalava T, Weivoda MM, Hachfeld CM, Prata LG, van Dijk TH, Verkade E, Casaclang-Verzosa G, Johnson KO, Cubro H, Doornebal EJ, Ogrodnik M, Jurk D, Jensen MD, Chini EN, Miller JD, Matveyenko A, Stout MB, Schafer MJ, White TA, Hickson LJ, Demaria M, Garovic V, Grande J, Arriaga EA, Kuipers F, von Zglinicki T, LeBrasseur NK, Campisi J, Tchkonia T, Kirkland JL. Targeting senescent cells alleviates obesity-induced metabolic dysfunction. Aging Cell. 2019 Jun; 18 (3):e12950 Epub 2019 Mar 25 View PubMed Chen Y, Harty GJ, Zheng Y, Iyer SR, Sugihara S, Sangaralingham SJ, Ichiki T, Grande JP, Lee HC, Wang XL, Burnett JC Jr. CRRL269. Circ Res. 2019 May 10; 124 (10):1462-1472 View PubMed D'Costa MR, Dalvin LA, Manohar S, Maguire LJ, Grande JP, Gonsalves WI, Nasr SH, Hogan MC. Crystalglobulin-Induced Nephropathy and Keratopathy. Kidney Med. 2019 Mar-Apr; 1 (2):71-74 Epub 2019 Feb 25 View PubMed Gonzalez Suarez ML, Kattah A, Grande JP, Garovic V. Renal Disorders in Pregnancy: Core Curriculum 2019. Am J Kidney Dis. 2019 Jan; 73 (1):119-130 Epub 2018 Aug 16 View PubMed Wang Y, Wang E, Zhang Y, Madamsetty VS, Ji B, Radisky DC, Grande JP, Misra S, Mukhopadhyay D. Neuropilin-1 maintains dimethylarginine dimethylaminohydrolase 1 expression in endothelial cells, and contributes to protection from angiotensin II-induced hypertension. FASEB J. 2019 Jan; 33 (1):494-500 Epub 2018 Aug 17 View PubMed Nath KA, O'Brien DR, Croatt AJ, Grande JP, Ackerman AW, Nath MC, Yamada S, Terzic A, Tchkonia T, Kirkland JL, Katusic ZS. The murine dialysis fistula model exhibits a senescence phenotype: pathobiological mechanisms and therapeutic potential. Am J Physiol Renal Physiol. 2018 Nov 1; 315 (5):F1493-F1499 Epub 2018 July 18 View PubMed Puranik AS, Leaf IA, Jensen MA, Hedayat AF, Saad A, Kim KW, Saadalla AM, Woollard JR, Kashyap S, Textor SC, Grande JP, Lerman A, Simari RD, Randolph GJ, Duffield JS, Lerman LO. Kidney-resident macrophages promote a proangiogenic environment in the normal and chronically ischemic mouse kidney. Sci Rep. 2018 Sep 17; 8 (1):13948 Epub 2018 Sept 17 View PubMed Thompson SM, Jondal DE, Butters KA, Knudsen BE, Anderson JL, Stokes MP, Jia X, Grande JP, Roberts LR, Callstrom MR, Woodrum DA. Heat stress induced, ligand-independent MET and EGFR signalling in hepatocellular carcinoma. Int J Hyperthermia. 2018 Sep; 34 (6):812-823 Epub 2017 Nov 06 View PubMed Alexander MP, Dasari S, Vrana JA, Riopel J, Valeri AM, Markowitz GS, Hever A, Bijol V, Larsen CP, Cornell LD, Fidler ME, Said SM, Sethi S, Herrera Hernandez LP, Grande JP, Erickson SB, Fervenza FC, Leung N, Kurtin PJ, Nasr SH. Congophilic Fibrillary Glomerulonephritis: A Case Series. Am J Kidney Dis. 2018 Sep; 72 (3):325-336 Epub 2018 June 14 View PubMed Kashyap S, Osman M, Ferguson CM, Nath MC, Roy B, Lien KR, Nath KA, Garovic VD, Lerman LO, Grande JP. Ccl2 deficiency protects against chronic renal injury in murine renovascular hypertension. Sci Rep. 2018 Jun 5; 8 (1):8598 Epub 2018 June 05 View PubMed Gaston RS, Fieberg A, Hunsicker L, Kasiske BL, Leduc R, Cosio FG, Gourishankar S, Grande J, Mannon RB, Rush D, Cecka JM, Connett J, Matas AJ. Late graft failure after kidney transplantation as the consequence of late versus early events. Am J Transplant. 2018 May; 18 (5):1158-1167 Epub 2017 Dec 05 View PubMed Nath KA, Belcher JD, Nath MC, Grande JP, Croatt AJ, Ackerman AW, Katusic ZS, Vercellotti GM. Role of TLR4 signaling in the nephrotoxicity of heme and heme proteins. Am J Physiol Renal Physiol. 2018 May 1; 314 (5):F906-F914 Epub 2017 Oct 04 View PubMed Nasr SH, Vrana JA, Dasari S, Bridoux F, Fidler ME, Kaaki S, Quellard N, Rinsant A, Goujon JM, Sethi S, Fervenza FC, Cornell LD, Said SM, McPhail ED, Herrera Hernandez LP, Grande JP, Hogan MC, Lieske JC, Leung N, Kurtin PJ, Alexander MP. DNAJB9 Is a Specific Immunohistochemical Marker for Fibrillary Glomerulonephritis. Kidney Int Rep. 2018 Jan; 3 (1):56-64 Epub 2017 Aug 08 View PubMed Sekulic M, Nasr SH, Grande JP, Cornell LD. Histologic regression of fibrillary glomerulonephritis: the first report of biopsy-proven spontaneous resolution of disease. Clin Kidney J. 2017 Dec; 10 (6):738-741 Epub 2017 June 05 View PubMed Gilani SI, Anderson UD, Jayachandran M, Weissgerber TL, Zand L, White WM, Milic N, Suarez Gonzalez ML, Vallapureddy RR, Naav A, Erlandsson L, Lieske JC, Grande JP, Nath KA, Hansson SR, Garovic VD. Urinary Extracellular Vesicles of Podocyte Origin and Renal Injury in Preeclampsia. J Am Soc Nephrol. 2017 Nov; 28 (11):3363-3372 Epub 2017 July 20 View PubMed Manohar S, Sathick IJ, Grande J, El-Zoghby Z, Leung N. An Unusual Case of Acute Myeloid Leukemia Cell Infiltration of the Renal Allograft: A Case Report and Review of Literature. Transplant Proc. 2017 Sep; 49 (7):1578-1582 View PubMed Jiang K, Ferguson CM, Ebrahimi B, Tang H, Kline TL, Burningham TA, Mishra PK, Grande JP, Macura SI, Lerman LO. Noninvasive Assessment of Renal Fibrosis with Magnetization Transfer MR Imaging: Validation and Evaluation in Murine Renal Artery Stenosis. Radiology. 2017 Apr; 283 (1):77-86 Epub 2016 Oct 03 View PubMed Kashyap S, Warner G, Hu Z, Gao F, Osman M, Al Saiegh Y, Lien KR, Nath K, Grande JP. Cardiovascular phenotype in Smad3 deficient mice with renovascular hypertension. PLoS One. 2017; 12 (10):e0187062 Epub 2017 Oct 26 View PubMed Kashyap S, Boyilla R, Zaia PJ, Ghossan R, Nath KA, Textor SC, Lerman LO, Grande JP. Development of renal atrophy in murine 2 kidney 1 clip hypertension is strain independent. Res Vet Sci. 2016 Aug; 107:171-177 Epub 2016 June 08 View PubMed Patil CN, Wallace K, LaMarca BD, Moulana M, Lopez-Ruiz A, Soljancic A, Juncos LA, Grande JP, Reckelhoff JF. Low-dose testosterone protects against renal ischemia-reperfusion injury by increasing renal IL-10-to-TNF-alpha ratio and attenuating T-cell infiltration. Am J Physiol Renal Physiol. 2016 Aug 1; 311 (2):F395-403 Epub 2016 June 01 View PubMed Casey PM, Palmer BA, Thompson GB, Laack TA, Thomas MR, Hartz MF, Jensen JR, Sandefur BJ, Hammack JE, Swanson JW, Sheeler RD, Grande JP. Predictors of medical school clerkship performance: a multispecialty longitudinal analysis of standardized examination scores and clinical assessments. BMC Med Educ. 2016 Apr 27; 16:128 View PubMed Kang L, Grande JP, Hillestad ML, Croatt AJ, Barry MA, Katusic ZS, Nath KA. A new model of an arteriovenous fistula in chronic kidney disease in the mouse: beneficial effects of upregulated heme oxygenase-1. Am J Physiol Renal Physiol. 2016 Mar 15; 310 (6):F466-76 Epub 2015 Dec 16 View PubMed Kashyap S, Warner GM, Hartono SP, Boyilla R, Knudsen BE, Zubair AS, Lien K, Nath KA, Textor SC, Lerman LO, Grande JP. Blockade of CCR2 reduces macrophage influx and development of chronic renal damage in murine renovascular hypertension. Am J Physiol Renal Physiol. 2016 Mar 1; 310 (5):F372-84 Epub 2015 Dec 09 View PubMed Kim TD, Jin F, Shin S, Oh S, Lightfoot SA, Grande JP, Johnson AJ, van Deursen JM, Wren JD, Janknecht R. Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1. J Clin Invest. 2016 Feb 1; 126: (2)706-20. View PubMed Thompson SM, Callstrom MR, Jondal DE, Butters KA, Knudsen BE, Anderson JL, Lien KR, Sutor SL, Lee JS, Thorgeirsson SS, Grande JP, Roberts LR, Woodrum DA. Heat Stress-Induced PI3K/mTORC2-Dependent AKT Signaling Is a Central Mediator of Hepatocellular Carcinoma Survival to Thermal Ablation Induced Heat Stress. PLoS One. 2016; 11 (9):e0162634 Epub 2016 Sept 09 View PubMed Peacock JG, Grande JP. An online app platform enhances collaborative medical student group learning and classroom management. Med Teach. 2016; 38: (2)174-80. View PubMed Kashyap S, Engel S, Osman M, Al-Saiegh Y, Wongjarupong A, Grande JP. Cardiovascular manifestations of renovascular hypertension in diabetic mice. PeerJ. 2016; 4:e1736 Epub 2016 Feb 22 View PubMed Chowdhary VR, Dai C, Tilahun AY, Hanson JA, Smart MK, Grande JP, Rajagopalan G, Fu SM, David CS. A Central Role for HLA-DR3 in Anti-Smith Antibody Responses and Glomerulonephritis in a Transgenic Mouse Model of Spontaneous Lupus. J Immunol. 2015 Nov 15; 195 (10):4660-7 Epub 2015 Oct 16 View PubMed Zand L, Monaghan M, Griffin BR, Wagner SJ, Criaci IM, Kamal A, Raissian Y, Grande JP, Lim KG, Garovic VD. The role of type i hypersensitivity reaction and ige-mediated mast cell activation in acute interstitial nephritis. Clin Nephrol. 2015 Sep; 84(3):138-44. View PubMed Peacock JG, Grande JP. A flexible, preclinical, medical school curriculum increases student academic productivity and the desire to conduct future research. Biochem Mol Biol Educ. 2015 Sep-Oct; 43: (5)384-90. View PubMed Zhou X, Merchak K, Lee W, Grande JP, Cascalho M, Platt JL. Cell Fusion Connects Oncogenesis with Tumor Evolution. Am J Pathol. 2015 Jul; 185 (7):2049-60 Epub 2015 June 08 View PubMed Kang L, Hillestad ML, Grande JP, Croatt AJ, Barry MA, Farrugia G, Katusic ZS, Nath KA. Induction and functional significance of the heme oxygenase system in pathological shear stress in vivo. Am J Physiol Heart Circ Physiol. 2015 Jun 1; 308 (11):H1402-13 Epub 2015 Mar 27 View PubMed Hwang SM, Kuyava JM, Grande JP, Swetz KM. Metastatic renal cell carcinoma mimicking diverticulitis in a patient with chronic lymphocytic leukaemia. BMJ Case Rep. 2015 Jan 7; 2015 Epub 2015 Jan 07 View PubMed Peacock JG, Grande JP. Patient exposure in the basic science classroom enhances differential diagnosis formation and clinical decision-making. PeerJ. 2015; 3:e809 Epub 2015 Feb 26 View PubMed Thompson SM, Callstrom MR, Butters KA, Sutor SL, Knudsen B, Grande JP, Roberts LR, Woodrum DA. Role for putative hepatocellular carcinoma stem cell subpopulations in biological response to incomplete thermal ablation: in vitro and in vivo pilot study. Cardiovasc Intervent Radiol. 2014 Oct; 37 (5):1343-51 Epub 2014 Jan 23 View PubMed Al-Suraih M, Grande JP. Management of renal artery stenosis: What does the experimental evidence tell us? World J Cardiol. 2014 Aug 26; 6 (8):855-60 View PubMed Craici IM, Wagner SJ, Weissgerber TL, Grande JP, Garovic VD. Advances in the pathophysiology of pre-eclampsia and related podocyte injury. Kidney Int. 2014 Aug; 86 (2):275-85 Epub 2014 Feb 26 View PubMed Poterucha TJ, Wetter DA, Grande JP, Gibson LE, Camilleri MJ, Lohse CM. A retrospective comparison of skin and renal direct immunofluorescence findings in patients with glomerulonephritis in adult Henoch-Schonlein purpura. J Cutan Pathol. 2014 Jul; 41 (7):582-7 View PubMed Kim H, Zhen DB, Lieske JC, McBane RD, Grande JP, Sandhu GS, Melduni RM. Treatment of Cholesterol Embolization Syndrome in the Setting of an Acute Indication for Anticoagulation Therapy. J Med Cases. 2014 Jun 1; 5 (6):376-379 View PubMed Hartono SP, Knudsen BE, Lerman LO, Textor SC, Grande JP. Combined effect of hyperfiltration and renin angiotensin system activation on development of chronic kidney disease in diabetic db/db mice. BMC Nephrol. 2014 Apr 4; 15:58 Epub 2014 Apr 04 View PubMed Thompson SM, Callstrom MR, Butters KA, Knudsen B, Grande JP, Roberts LR, Woodrum DA. Heat stress induced cell death mechanisms in hepatocytes and hepatocellular carcinoma: in vitro and in vivo study. Lasers Surg Med. 2014 Apr; 46 (4):290-301 Epub 2014 Mar 18 View PubMed Sterner RM, Hartono SP, Grande JP. The Pathogenesis of Lupus Nephritis. J Clin Cell Immunol. 2014 Apr; 5 (2) View PubMed Eirin A, Zhang X, Zhu XY, Tang H, Jordan KL, Grande JP, Dietz AB, Lerman A, Textor SC, Lerman LO. Renal vein cytokine release as an index of renal parenchymal inflammation in chronic experimental renal artery stenosis. Nephrol Dial Transplant. 2014 Feb; 29 (2):274-82 Epub 2013 Oct 03 View PubMed Hayman SR, Calle JC, Jatoi A, Craici IM, Wagner SJ, Weaver AL, Greene EL, Grande JP, Garovic VD. Urinary podocyte excretion and proteinuria in patients treated with antivascular endothelial growth factor therapy for solid tumor malignancies. Oncology. 2014; 86 (5-6):271-8 Epub 2014 June 04 View PubMed White WM, Garrett AT, Craici IM, Wagner SJ, Fitz-Gibbon PD, Butters KA, Brost BC, Rose CH, Grande JP, Garovic VD. Persistent urinary podocyte loss following preeclampsia may reflect subclinical renal injury. PLoS One. 2014; 9 (3):e92693 Epub 2014 Mar 24 View PubMed Peacock JG, Grande JP. The impact of specialty choice on medical student research Medical Science Educator. 2014; 24 (Suppl 1):19-20 Ebrahimi B, Crane JA, Knudsen BE, Macura SI, Grande JP, Lerman LO. Evolution of cardiac and renal impairment detected by high-field cardiovascular magnetic resonance in mice with renal artery stenosis. J Cardiovasc Magn Reson. 2013 Oct 26; 15 (1):98 View PubMed Hartono SP, Knudsen BE, Zubair AS, Nath KA, Textor SJ, Lerman LO, Grande JP. Redox signaling is an early event in the pathogenesis of renovascular hypertension. Int J Mol Sci. 2013 Sep 10; 14 (9):18640-56 Epub 2013 Sept 10 View PubMed El Ters M, Grande JP, Keddis MT, Rodrigo E, Chopra B, Dean PG, Stegall MD, Cosio FG. Kidney allograft survival after acute rejection, the value of follow-up biopsies. Am J Transplant. 2013 Sep; 13 (9):2334-41 Epub 2013 July 19 View PubMed Franchi F, Knudsen BE, Oehler E, Textor SC, Lerman LO, Grande JP, Rodriguez-Porcel M. Non-invasive assessment of cardiac function in a mouse model of renovascular hypertension. Hypertens Res. 2013 Sep; 36 (9):770-5 Epub 2013 May 16 View PubMed Kang L, Grande JP, Farrugia G, Croatt AJ, Katusic ZS, Nath KA. Functioning of an arteriovenous fistula requires heme oxygenase-2. Am J Physiol Renal Physiol. 2013 Aug 15; 305 (4):F545-52 Epub 2013 May 15 View PubMed Thompson SM, Callstrom MR, Knudsen BE, Anderson JL, Sutor SL, Butters KA, Kuo C, Grande JP, Roberts LR, Woodrum DA. Molecular bioluminescence imaging as a noninvasive tool for monitoring tumor growth and therapeutic response to MRI-guided laser ablation in a rat model of hepatocellular carcinoma. Invest Radiol. 2013 Jun; 48 (6):413-21 View PubMed Garovic VD, Craici IM, Wagner SJ, White WM, Brost BC, Rose CH, Grande JP, Barnidge DR. Mass spectrometry as a novel method for detection of podocyturia in pre-eclampsia. Nephrol Dial Transplant. 2013 Jun; 28 (6):1555-61 Epub 2012 Apr 20 View PubMed Craici IM, Wagner SJ, Bailey KR, Fitz-Gibbon PD, Wood-Wentz CM, Turner ST, Hayman SR, White WM, Brost BC, Rose CH, Grande JP, Garovic VD. Podocyturia predates proteinuria and clinical features of preeclampsia: longitudinal prospective study. Hypertension. 2013 Jun; 61(6):1289-96. Epub 2013 Mar 25. View PubMed Eirin A, Zhu XY, Li Z, Ebrahimi B, Zhang X, Tang H, Korsmo MJ, Chade AR, Grande JP, Ward CJ, Simari RD, Lerman A, Textor SC, Lerman LO. Endothelial outgrowth cells shift macrophage phenotype and improve kidney viability in swine renal artery stenosis. Arterioscler Thromb Vasc Biol. 2013 May; 33 (5):1006-13 Epub 2013 Feb 21 View PubMed Ryan ZC, Ketha H, McNulty MS, McGee-Lawrence M, Craig TA, Grande JP, Westendorf JJ, Singh RJ, Kumar R. Sclerostin alters serum vitamin D metabolite and fibroblast growth factor 23 concentrations and the urinary excretion of calcium. Proc Natl Acad Sci U S A. 2013 Apr 9; 110 (15):6199-204 Epub 2013 Mar 25 View PubMed Gloviczki ML, Keddis MT, Garovic VD, Friedman H, Herrmann S, McKusick MA, Misra S, Grande JP, Lerman LO, Textor SC. TGF expression and macrophage accumulation in atherosclerotic renal artery stenosis. Clin J Am Soc Nephrol. 2013 Apr; 8 (4):546-53 Epub 2012 Dec 20 View PubMed Rogozina OP, Nkhata KJ, Nagle EJ, Grande JP, Cleary MP. The protective effect of intermittent calorie restriction on mammary tumorigenesis is not compromised by consumption of a high fat diet during refeeding. Breast Cancer Res Treat. 2013 Apr; 138(2):395-406. Epub 2013 Feb 28. View PubMed Wang D, Warner GM, Yin P, Knudsen BE, Cheng J, Butters KA, Lien KR, Gray CE, Garovic VD, Lerman LO, Textor SC, Nath KA, Simari RD, Grande JP. Inhibition of p38 MAPK attenuates renal atrophy and fibrosis in a murine renal artery stenosis model. Am J Physiol Renal Physiol. 2013 Apr 1; 304 (7):F938-47 Epub 2013 Jan 30 View PubMed Peacock JG, Warner LL, Drozdowicz LB, Martin BA, Suresh R, Denzer BJ, Wentworth AB, Adefusika JA, Bachman MJ, Grande JP. Curricular flexibility in the pre-clinical years promotes medical student scholarship. Medical Science Educator. 2013 March; 23(1S):92-98. Nath KA, Grande JP, Farrugia G, Croatt AJ, Belcher JD, Hebbel RP, Vercellotti GM, Katusic ZS. Age sensitizes the kidney to heme protein-induced acute kidney injury. Am J Physiol Renal Physiol. 2013 Feb 1; 304 (3):F317-25 Epub 2012 Nov 28 View PubMed Thompson SM, Callstrom MR, Knudsen B, Anderson JL, Butters KA, Grande JP, Roberts LR, Woodrum DA. AS30D model of hepatocellular carcinoma: tumorigenicity and preliminary characterization by imaging, histopathology, and immunohistochemistry. Cardiovasc Intervent Radiol. 2013 Feb; 36 (1):198-203 Epub 2012 Aug 25 View PubMed Eirin A, Gloviczki ML, Tang H, Gossl M, Jordan KL, Woollard JR, Lerman A, Grande JP, Textor SC, Lerman LO. Inflammatory and injury signals released from the post-stenotic human kidney. Eur Heart J. 2013 Feb; 34 (7):540-548a Epub 2012 July 06 View PubMed Newcomer KL, Laskowski ER, Grande JP, Dyrbye LN. The physiatrists' crucial role in the development and implementation of a longitudinal musculoskeletal physical examination curriculum in a medical school. Am J Phys Med Rehabil. 2013 Jan; 92: (1)84-9. View PubMed Ebrahimi B, Macura SI, Knudsen BE, Grande JP, Lerman LO. Fibrosis detection in renal artery stenosis mouse model using magnetization transfer MRI. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2013; 8672:867205. Tsapenko MV, d'Uscio LV, Grande JP, Croatt AJ, Hernandez MC, Ackerman AW, Katusic ZS, Nath KA. Increased production of superoxide anion contributes to dysfunction of the arteriovenous fistula. Am J Physiol Renal Physiol. 2012 Dec 15; 303(12):F1601-7. Epub 2012 Sep 19 View PubMed Wagner SJ, Craici IM, Grande JP, Garovic VD. From placenta to podocyte: vascular and podocyte pathophysiology in preeclampsia. Clin Nephrol. 2012 Sep; 78 (3):241-9 View PubMed Chowdhary VR, Tilahun AY, Clark CR, Grande JP, Rajagopalan G. Chronic exposure to staphylococcal superantigen elicits a systemic inflammatory disease mimicking lupus. J Immunol. 2012 Aug 15; 189 (4):2054-62 Epub 2012 July 13 View PubMed Hayman SR, Leung N, Grande JP, Garovic VD. VEGF inhibition, hypertension, and renal toxicity. Curr Oncol Rep. 2012 Aug; 14 (4):285-94 View PubMed Warner GM, Cheng J, Knudsen BE, Gray CE, Deibel A, Juskewitch JE, Lerman LO, Textor SC, Nath KA, Grande JP. Genetic deficiency of Smad3 protects the kidneys from atrophy and interstitial fibrosis in 2K1C hypertension. Am J Physiol Renal Physiol. 2012 Jun 1; 302 (11):F1455-64 Epub 2012 Feb 29 View PubMed Eirin A, Zhu XY, Krier JD, Tang H, Jordan KL, Grande JP, Lerman A, Textor SC, Lerman LO. Adipose tissue-derived mesenchymal stem cells improve revascularization outcomes to restore renal function in swine atherosclerotic renal artery stenosis. Stem Cells. 2012 May; 30 (5):1030-41 View PubMed Rodriguez EF, Cosio FG, Nasr SH, Sethi S, Fidler ME, Stegall MD, Grande JP, Fervenza FC, Cornell LD. The pathology and clinical features of early recurrent membranous glomerulonephritis. Am J Transplant. 2012 Apr; 12 (4):1029-38 Epub 2012 Jan 10 View PubMed Thompson SM, Callstrom MR, Knudsen B, Anderson JL, Carter RE, Grande JP, Roberts LR, Woodrum DA. Development and preliminary testing of a translational model of hepatocellular carcinoma for MR imaging and interventional oncologic investigations. J Vasc Interv Radiol. 2012 Mar; 23 (3):385-95 Epub 2012 Jan 20 View PubMed Textor SC, Gloviczki ML, Flessner MF, Calhoun DA, Glockner J, Grande JP, McKusick MA, Cha SS, Lerman LO. Association of filtered sodium load with medullary volumes and medullary hypoxia in hypertensive African Americans as compared with whites. Am J Kidney Dis. 2012 Feb; 59 (2):229-37 Epub 2011 Nov 29 View PubMed Garovic VD, Edukulla R, White WM, Rose CH, Brost BC, Watson WJ, Craici IM, Wagner SJ, Grande JP. Flow cytometry as a novel method for detection of podocyturia in preeclampsia. American Journal of Obstetrics and Gynecology. 2012; 206(1):S349-S350. Sandefur M, Blustin J, Juskewitch J, Aberle S, Angstman E, Warner P, Pawlina W, Grande J. The effects of first year medical students' gender and career interest on educational gains from longitudinal cases. Medical Science Educator. 2012; 22(1):2-9. Juskewitch JE, Platt JL, Knudsen BE, Knutson KL, Brunn GJ, Grande JP. Disparate roles of marrow- and parenchymal cell-derived TLR4 signaling in murine LPS-induced systemic inflammation. Sci Rep. 2012; 2:918 Epub 2012 Dec 04 View PubMed Liang KV, Grande JP, Fidler ME, Garovic VD. Levofloxacin-induced acute interstitial nephritis. Gazzetta Medica Italiana Archivio per le Scienze Mediche. 2012; 171(2):227-31. Juskewitch JE, Knudsen BE, Platt JL, Nath KA, Knutson KL, Brunn GJ, Grande JP. LPS-induced murine systemic inflammation is driven by parenchymal cell activation and exclusively predicted by early MCP-1 plasma levels. Am J Pathol. 2012 Jan; 180 (1):32-40 Epub 2011 Nov 07 View PubMed Gloviczki ML, Glockner JF, Crane JA, McKusick MA, Misra S, Grande JP, Lerman LO, Textor SC. Blood oxygen level-dependent magnetic resonance imaging identifies cortical hypoxia in severe renovascular disease. Hypertension. 2011 Dec; 58 (6):1066-72 Epub 2011 Oct 31 View PubMed Sangaralingham SJ, Heublein DM, Grande JP, Cataliotti A, Rule AD, McKie PM, Martin FL, Burnett JC Jr. Urinary C-type natriuretic peptide excretion: a potential novel biomarker for renal fibrosis during aging. Am J Physiol Renal Physiol. 2011 Nov; 301 (5):F943-52 Epub 2011 Aug 24 View PubMed Li Z, Woollard JR, Wang S, Korsmo MJ, Ebrahimi B, Grande JP, Textor SC, Lerman A, Lerman LO. Increased glomerular filtration rate in early metabolic syndrome is associated with renal adiposity and microvascular proliferation. Am J Physiol Renal Physiol. 2011 Nov; 301 (5):F1078-87 Epub 2011 July 20 View PubMed Said SM, Leung N, Sethi S, Cornell LD, Fidler ME, Grande JP, Herrmann S, Tefferi A, D'Agati VD, Nasr SH. Myeloproliferative neoplasms cause glomerulopathy. Kidney Int. 2011 Oct; 80(7):753-9. Epub 2011 Jun 8 View PubMed Kang L, Yamada S, Hernandez MC, Croatt AJ, Grande JP, Juncos JP, Vercellotti GM, Hebbel RP, Katusic ZS, Terzic A, Nath KA. Regional and systemic hemodynamic responses following the creation of a murine arteriovenous fistula. Am J Physiol Renal Physiol. 2011 Oct; 301 (4):F845-51 Epub 2011 June 22 View PubMed Thompson SM, Ramirez-Giraldo JC, Knudsen B, Grande JP, Christner JA, Xu M, Woodrum DA, McCollough CH, Callstrom MR. Porcine ex vivo liver phantom for dynamic contrast-enhanced computed tomography: development and initial results. Invest Radiol. 2011 Sep; 46 (9):586-93 View PubMed Nath KA, Croatt AJ, Warner GM, Grande JP. Genetic deficiency of Smad3 protects against murine ischemic acute kidney injury. Am J Physiol Renal Physiol. 2011 Aug; 301 (2):F436-42 Epub 2011 Apr 27 View PubMed Eirin A, Zhu XY, Urbieta-Caceres VH, Grande JP, Lerman A, Textor SC, Lerman LO. Persistent kidney dysfunction in swine renal artery stenosis correlates with outer cortical microvascular remodeling. Am J Physiol Renal Physiol. 2011 Jun; 300 (6):F1394-401 Epub 2011 Mar 02 View PubMed Noppakun K, Cosio FG, Dean PG, Taler SJ, Wauters R, Grande JP. Living donor age and kidney transplant outcomes. Am J Transplant. 2011 Jun; 11 (6):1279-86 Epub 2011 May 12 View PubMed Diaz Encarnacion MM, Warner GM, Cheng J, Gray CE, Nath KA, Grande JP. n-3 Fatty acids block TNF-alpha-stimulated MCP-1 expression in rat mesangial cells. Am J Physiol Renal Physiol. 2011 May; 300 (5):F1142-51 Epub 2011 Mar 02 View PubMed Rogozina OP, Bonorden MJ, Seppanen CN, Grande JP, Cleary MP. Effect of chronic and intermittent calorie restriction on serum adiponectin and leptin and mammary tumorigenesis. Cancer Prev Res (Phila). 2011 Apr; 4(4):568-81. Epub 2011 Jan 21. View PubMed Grande JP. Experimental models of lupus nephritis. Contrib Nephrol. 2011; 169:183-197 Epub 2011 Jan 20 View PubMed Juncos JP, Grande JP, Kang L, Ackerman AW, Croatt AJ, Katusic ZS, Nath KA. MCP-1 contributes to arteriovenous fistula failure. J Am Soc Nephrol. 2011 Jan; 22 (1):43-8 Epub 2010 Nov 29 View PubMed Dogan S, Johannsen AC, Grande JP, Cleary MP. Effects of intermittent and chronic calorie restriction on mammalian target of rapamycin (mTOR) and IGF-I signaling pathways in mammary fat pad tissues and mammary tumors. Nutr Cancer. 2011; 63(3):389-401. View PubMed Nath KA, Grande JP, Kang L, Juncos JP, Ackerman AW, Croatt AJ, Katusic ZS. ss-Catenin is markedly induced in a murine model of an arteriovenous fistula: the effect of metalloproteinase inhibition. Am J Physiol Renal Physiol. 2010 Dec; 299 (6):F1270-7 Epub 2010 Sept 29 View PubMed Crary GS, Raissian Y, Gaston RC, Gourishankar SM, Leduc RE, Mannon RB, Matas AJ, Grande JP. Optimal cutoff point for immunoperoxidase detection of C4d in the renal allograft: results from a multicenter study. Transplantation. 2010 Nov 27; 90(10):1099-105. View PubMed Keddis MT, Garovic VD, Bailey KR, Wood CM, Raissian Y, Grande JP. Ischaemic nephropathy secondary to atherosclerotic renal artery stenosis: clinical and histopathological correlates. Nephrol Dial Transplant. 2010 Nov; 25(11):3615-22. Epub 2010 May 25. View PubMed Mannon RB, Matas AJ, Grande J, Leduc R, Connett J, Kasiske B, Cecka JM, Gaston RS, Cosio F, Gourishankar S, Halloran PF, Hunsicker L, Rush D, DeKAF Investigators. Inflammation in areas of tubular atrophy in kidney allograft biopsies: a potent predictor of allograft failure. Am J Transplant. 2010 Sep; 10(9):2066-73. View PubMed Porter BL, Grande JP. Mayo Medical School. Acad Med. 2010 Sep; 85(9 Suppl):S300-4. View PubMed Gaston RS, Cecka JM, Kasiske BL, Fieberg AM, Leduc R, Cosio FC, Gourishankar S, Grande J, Halloran P, Hunsicker L, Mannon R, Rush D, Matas AJ. Evidence for antibody-mediated injury as a major determinant of late kidney allograft failure. Transplantation. 2010 Jul 15; 90(1):68-74. View PubMed Chade AR, Zhu XY, Krier JD, Jordan KL, Textor SC, Grande JP, Lerman A, Lerman LO. Endothelial progenitor cells homing and renal repair in experimental renovascular disease. Stem Cells. 2010 Jun; 28 (6):1039-47 View PubMed Rashtak S, Marietta E, Cheng S, Camilleri M, Pittelkow M, David C, Grande J, Murray J. Spontaneous lupus-like syndrome in HLA-DQ2 transgenic mice with a mixed genetic background. Lupus. 2010 Jun; 19 (7):815-29 Epub 2010 Feb 08 View PubMed Croatt AJ, Grande JP, Hernandez MC, Ackerman AW, Katusic ZS, Nath KA. Characterization of a model of an arteriovenous fistula in the rat: the effect of L-NAME. Am J Pathol. 2010 May; 176 (5):2530-41 Epub 2010 Apr 02 View PubMed Juncos JP, Grande JP, Croatt AJ, Hebbel RP, Vercellotti GM, Katusic ZS, Nath KA. Early and prominent alterations in hemodynamics, signaling, and gene expression following renal ischemia in sickle cell disease. Am J Physiol Renal Physiol. 2010 Apr; 298 (4):F892-9 Epub 2010 Jan 27 View PubMed Gloviczki ML, Glockner JF, Lerman LO, McKusick MA, Misra S, Grande JP, Textor SC. Preserved oxygenation despite reduced blood flow in poststenotic kidneys in human atherosclerotic renal artery stenosis. Hypertension. 2010 Apr; 55 (4):961-6 Epub 2010 Mar 01 View PubMed Matas AJ, Leduc R, Rush D, Cecka JM, Connett J, Fieberg A, Halloran P, Hunsicker L, Cosio F, Grande J, Mannon R, Gourishankar S, Gaston R, Kasiske B. Histopathologic clusters differentiate subgroups within the nonspecific diagnoses of CAN or CR: preliminary data from the DeKAF study. Am J Transplant. 2010 Feb; 10(2):315-23. Epub 2009 Dec 23. View PubMed Gourishankar S, Leduc R, Connett J, Cecka JM, Cosio F, Fieberg A, Gaston R, Halloran P, Hunsicker L, Kasiske B, Rush D, Grande J, Mannon R, Matas A. Pathological and clinical characterization of the 'troubled transplant': data from the DeKAF study. Am J Transplant. 2010 Feb; 10(2):324-30. Epub 2010 Jan 05. View PubMed Mooney SM, Grande JP, Salisbury JL, Janknecht R. Sumoylation of p68 and p72 RNA helicases affects protein stability and transactivation potential. Biochemistry. 2010 Jan 12; 49 (1):1-10 View PubMed Dogan S, Rogozina OP, Lokshin AE, Grande JP, Cleary MP. Effects of chronic vs. intermittent calorie restriction on mammary tumor incidence and serum adiponectin and leptin levels in MMTV-TGF-alpha mice at different ages. Oncol Lett. 2010 Jan; 1(1):167-76. Epub 2010 Jan 01. View PubMed El-Zoghby ZM, Grande JP, Fraile MG, Norby SM, Fervenza FC, Cosio FG. Recurrent idiopathic membranous nephropathy: early diagnosis by protocol biopsies and treatment with anti-CD20 monoclonal antibodies. Am J Transplant. 2009 Dec; 9 (12):2800-7 Epub 2009 Oct 21 View PubMed Lerman LO, Textor SC, Grande JP. Mechanisms of tissue injury in renal artery stenosis: ischemia and beyond. Prog Cardiovasc Dis. 2009 Nov-Dec; 52 (3):196-203 View PubMed Shin S, Kim TD, Jin F, van Deursen JM, Dehm SM, Tindall DJ, Grande JP, Munz JM, Vasmatzis G, Janknecht R. Induction of prostatic intraepithelial neoplasia and modulation of androgen receptor by ETS variant 1/ETS-related protein 81. Cancer Res. 2009 Oct 15; 69(20):8102-10. Epub 2009 Sep 29 View PubMed Cheng J, Zhou W, Warner GM, Knudsen BE, Garovic VD, Gray CE, Lerman LO, Platt JL, Romero JC, Textor SC, Nath KA, Grande JP. Temporal analysis of signaling pathways activated in a murine model of two-kidney, one-clip hypertension. Am J Physiol Renal Physiol. 2009 Oct; 297 (4):F1055-68 Epub 2009 July 22 View PubMed Maripuri S, Grande JP, Osborn TG, Fervenza FC, Matteson EL, Donadio JV, Hogan MC. Renal involvement in primary Sjogren's syndrome: a clinicopathologic study. Clin J Am Soc Nephrol. 2009 Sep; 4 (9):1423-31 Epub 2009 Aug 13 View PubMed Grande JP. Training of physicians for the twenty-first century: role of the basic sciences. Med Teach. 2009 Sep; 31 (9):802-6 View PubMed Rogozina OP, Bonorden MJ, Grande JP, Cleary MP. Serum insulin-like growth factor-I and mammary tumor development in ad libitum-fed, chronic calorie-restricted, and intermittent calorie-restricted MMTV-TGF-alpha mice. Cancer Prev Res (Phila Pa). 2009 Aug; 2: (8)712-9. View PubMed Wagner SJ, Craici I, Reed D, Norby S, Bailey K, Wiste HJ, Wood CM, Moder KG, Liang KP, Liang KV, Rose C, Rozkos T, Sitina M, Grande JP, Garovic VD. Maternal and foetal outcomes in pregnant patients with active lupus nephritis. Lupus. 2009 Apr; 18(4):342-7. View PubMed Nkhata KJ, Ray A, Dogan S, Grande JP, Cleary MP. Mammary tumor development from T47-D human breast cancer cells in obese ovariectomized mice with and without estradiol supplements. Breast Cancer Res Treat. 2009 Mar; 114(1):71-83. Epub 2008 Apr 06. View PubMed Bonorden MJ, Rogozina OP, Kluczny CM, Grossmann ME, Grande JP, Lokshin A, Cleary MP. Cross-sectional analysis of intermittent versus chronic caloric restriction in the TRAMP mouse. Prostate. 2009 Feb 15; 69(3):317-26. View PubMed Kurtz DM, Kruse JL, Schoenleber SJ, Grande JP. Students as teachers and course designers: Renovation of an introductory pathology course. JIAMSE. 2009; 19(1):8-14. Cheng J, Grande JP. Transforming growth factor-B and kidney dysfunction. Journal of Organ Dysfunction. 2009; 5(3):182-92. Bonorden MJ, Rogozina OP, Kluczny CM, Grossmann ME, Grambsch PL, Grande JP, Perkins S, Lokshin A, Cleary MP. Intermittent calorie restriction delays prostate tumor detection and increases survival time in TRAMP mice. Nutr Cancer. 2009; 61(2):265-75. View PubMed Tracz MJ, Juncos JP, Grande JP, Croatt AJ, Ackerman AW, Katusic ZS, Nath KA. Induction of heme oxygenase-1 is a beneficial response in a murine model of venous thrombosis. Am J Pathol. 2008 Dec; 173 (6):1882-90 Epub 2008 Nov 06 View PubMed Craig TA, Sommer S, Sussman CR, Grande JP, Kumar R. Expression and regulation of the vitamin D receptor in the zebrafish, Danio rerio. J Bone Miner Res. 2008 Sep; 23 (9):1486-96 View PubMed Chade AR, Zhu XY, Grande JP, Krier JD, Lerman A, Lerman LO. Simvastatin abates development of renal fibrosis in experimental renovascular disease. J Hypertens. 2008 Aug; 26 (8):1651-60 View PubMed Juncos JP, Tracz MJ, Croatt AJ, Grande JP, Ackerman AW, Katusic ZS, Nath KA. Genetic deficiency of heme oxygenase-1 impairs functionality and form of an arteriovenous fistula in the mouse. Kidney Int. 2008 Jul; 74 (1):47-51 Epub 2008 Mar 26 View PubMed Dabade TS, Grande JP, Norby SM, Fervenza FC, Cosio FG. Recurrent idiopathic membranous nephropathy after kidney transplantation: a surveillance biopsy study. Am J Transplant. 2008 Jun; 8 (6):1318-22 Epub 2008 Apr 29 View PubMed Diaz Encarnacion MM, Warner GM, Gray CE, Cheng J, Keryakos HK, Nath KA, Grande JP. Signaling pathways modulated by fish oil in salt-sensitive hypertension. Am J Physiol Renal Physiol. 2008 Jun; 294 (6):F1323-35 Epub 2008 Apr 02 View PubMed Dean PG, Grande JP, Sethi S, Park WD, Griffin MD, Cosio FG, Larson TS, Stegall MD. Kidney transplant histology after one year of continuous therapy with sirolimus compared with tacrolimus. Transplantation. 2008 Apr 27; 85(8):1212-5. View PubMed Textor SC, Glockner JF, Lerman LO, Misra S, McKusick MA, Riederer SJ, Grande JP, Gomez SI, Romero JC. The use of magnetic resonance to evaluate tissue oxygenation in renal artery stenosis. J Am Soc Nephrol. 2008 Apr; 19 (4):780-8 Epub 2008 Feb 20 View PubMed Tracz MJ, Juncos JP, Croatt AJ, Ackerman AW, Grande JP, Knutson KL, Kane GC, Terzic A, Griffin MD, Nath KA. Deficiency of heme oxygenase-1 impairs renal hemodynamics and exaggerates systemic inflammatory responses to renal ischemia. Kidney Int. 2007 Nov; 72 (9):1073-80 Epub 2007 Aug 29 View PubMed Chowdhary VR, Grande JP, Luthra HS, David CS. Characterization of haemorrhagic pulmonary capillaritis: another manifestation of Pristane-induced lupus. Rheumatology (Oxford). 2007 Sep; 46 (9):1405-10 Epub 2007 June 18 View PubMed Davis MH, Amin Z, Grande JP, O'Neill AE, Pawlina W, Viggiano TR, Zuberi R. Case studies in outcome-based education. Med Teach. 2007 Sep; 29(7):717-22. View PubMed Ray A, Nkhata KJ, Grande JP, Cleary MP. Diet-induced obesity and mammary tumor development in relation to estrogen receptor status. Cancer Lett. 2007 Aug 18; 253(2):291-300. Epub 2007 Mar 30. View PubMed Shin S, Rossow KL, Grande JP, Janknecht R. Involvement of RNA helicases p68 and p72 in colon cancer. Cancer Res. 2007 Aug 15; 67 (16):7572-8 View PubMed Caplice NM, Wang S, Tracz M, Croatt AJ, Grande JP, Katusic ZS, Nath KA. Neoangiogenesis and the presence of progenitor cells in the venous limb of an arteriovenous fistula in the rat. Am J Physiol Renal Physiol. 2007 Aug; 293 (2):F470-5 Epub 2007 Mar 06 View PubMed Park W, Griffin M, Grande JP, Cosio F, Stegall MD. Molecular evidence of injury and inflammation in normal and fibrotic renal allografts one year posttransplant. Transplantation. 2007 Jun 15; 83(11):1466-76. View PubMed Tracz MJ, Juncos JP, Grande JP, Croatt AJ, Ackerman AW, Rajagopalan G, Knutson KL, Badley AD, Griffin MD, Alam J, Nath KA. Renal hemodynamic, inflammatory, and apoptotic responses to lipopolysaccharide in HO-1-/- mice. Am J Pathol. 2007 Jun; 170 (6):1820-30 View PubMed Wadei HM, Amer H, Taler SJ, Cosio FG, Griffin MD, Grande JP, Larson TS, Schwab TR, Stegall MD, Textor SC. Diurnal blood pressure changes one year after kidney transplantation: relationship to allograft function, histology, and resistive index. J Am Soc Nephrol. 2007 May; 18: (5)1607-15. View PubMed Garovic VD, Wagner SJ, Petrovic LM, Gray CE, Hall P, Sugimoto H, Kalluri R, Grande JP. Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia. Nephrol Dial Transplant. 2007 Apr; 22 (4):1136-43 Epub 2007 Jan 25 View PubMed Garovic VD, Wagner SJ, Turner ST, Rosenthal DW, Watson WJ, Brost BC, Rose CH, Gavrilova L, Craigo P, Bailey KR, Achenbach J, Schiffer M, Grande JP. Urinary podocyte excretion as a marker for preeclampsia. Am J Obstet Gynecol. 2007 Apr; 196 (4):320.e1-7 View PubMed Cosio FG, Amer H, Grande JP, Larson TS, Stegall MD, Griffin MD. Comparison of low versus high tacrolimus levels in kidney transplantation: assessment of efficacy by protocol biopsies. Transplantation. 2007 Feb 27; 83 (4):411-6 View PubMed Ramos EJ, Pollinger HS, Stegall MD, Gloor JM, Dogan A, Grande JP. The effect of desensitization protocols on human splenic B-cell populations in vivo. Am J Transplant. 2007 Feb; 7 (2):402-7 View PubMed Murali NS, Ackerman AW, Croatt AJ, Cheng J, Grande JP, Sutor SL, Bram RJ, Bren GD, Badley AD, Alam J, Nath KA. Renal upregulation of HO-1 reduces albumin-driven MCP-1 production: implications for chronic kidney disease. Am J Physiol Renal Physiol. 2007 Feb; 292 (2):F837-44 Epub 2006 Sept 12 View PubMed Dogan S, Hu X, Zhang Y, Maihle NJ, Grande JP, Cleary MP. Effects of high-fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-alpha mice. Breast Cancer Res. 2007; 9(6):R91. View PubMed Cheng J, Grande JP. Cyclic nucleotide phosphodiesterase (PDE) inhibitors: novel therapeutic agents for progressive renal disease. Exp Biol Med (Maywood). 2007 Jan; 232(1):38-51. View PubMed Cleary MP, Hu X, Grossmann ME, Juneja SC, Dogan S, Grande JP, Maihle NJ. Prevention of mammary tumorigenesis by intermittent caloric restriction: Does caloric intake during refeeding modulate the response? Exp Biol Med. 2007 Jan; 232(1):70-80. View PubMed Thorsteinsdottir B, Kane GC, Hogan MJ, Watson WJ, Grande JP, Garovic VD. Adverse outcomes of renovascular hypertension during pregnancy. Nat Clin Pract Nephrol. 2006 Nov; 2: (11)651-6. View PubMed Rea DJ, Heimbach JK, Grande JP, Textor SC, Taler SJ, Prieto M, Larson TS, Cosio FG, Stegall MD. Glomerular volume and renal histology in obese and non-obese living kidney donors. Kidney Int. 2006 Nov; 70 (9):1636-41 Epub 2006 Sept 06 View PubMed Thorsteinsdottir B, Grande JP, Garovic VD. Acute renal failure in a young weight lifter taking multiple food supplements, including creatine monohydrate. J Ren Nutr. 2006 Oct; 16(4):341-5. View PubMed Donadio JV, Bergstralh EJ, Bibus DM, Grande JP. Is body size a biomarker for optimizing dosing of omega-3 polyunsaturated fatty acids in the treatment of patients with IgA nephropathy? Clin J Am Soc Nephrol. 2006 Sep; 1 (5):933-9 Epub 2006 Aug 02 View PubMed Malewicz B, Wang Z, Jiang C, Guo J, Cleary MP, Grande JP, Lu J. Enhancement of mammary carcinogenesis in two rodent models by silymarin dietary supplements. Carcinogenesis. 2006 Sep; 27(9):1739-47. Epub 2006 Apr 05. View PubMed Gloor JM, Cosio FG, Rea DJ, Wadei HM, Winters JL, Moore SB, DeGoey SR, Lager DJ, Grande JP, Stegall MD. Histologic findings one year after positive crossmatch or ABO blood group incompatible living donor kidney transplantation. Am J Transplant. 2006 Aug; 6 (8):1841-7 Epub 2006 June 19 View PubMed Juncos JP, Grande JP, Murali N, Croatt AJ, Juncos LA, Hebbel RP, Katusic ZS, Nath KA. Anomalous renal effects of tin protoporphyrin in a murine model of sickle cell disease. Am J Pathol. 2006 Jul; 169 (1):21-31 View PubMed Cheng J, Thompson MA, Walker HJ, Gray CE, Warner GM, Zhou W, Grande JP. Lixazinone stimulates mitogenesis of Madin-Darby canine kidney cells. Exp Biol Med (Maywood). 2006 Mar; 231 (3):288-95 View PubMed Sommer SL, Berndt TJ, Frank E, Patel JB, Redfield MM, Dong X, Griffin MD, Grande JP, van Deursen JM, Sieck GC, Romero JC, Kumar R. Elevated blood pressure and cardiac hypertrophy after ablation of the gly96/IEX-1 gene. J Appl Physiol (1985). 2006 Feb; 100: (2)707-16. View PubMed Pedraza-Chaverri J, Murali NS, Croatt AJ, Alam J, Grande JP, Nath KA. Proteinuria as a determinant of renal expression of heme oxygenase-1: studies in models of glomerular and tubular proteinuria in the rat. Am J Physiol Renal Physiol. 2006 Jan; 290 (1):F196-204 Epub 2005 Aug 23 View PubMed Gloor JM, Lager DJ, Fidler ME, Grande JP, Moore SB, Winters JL, Kremers WK, Stegall MD. A Comparison of splenectomy versus intensive posttransplant antidonor blood group antibody monitoring without splenectomy in ABO-incompatible kidney transplantation. Transplantation. 2005 Dec 15; 80 (11):1572-7 View PubMed Cosio FG, Grande JP, Wadei H, Larson TS, Griffin MD, Stegall MD. Predicting subsequent decline in kidney allograft function from early surveillance biopsies. Am J Transplant. 2005 Oct; 5 (10):2464-72 View PubMed Cheng J, Diaz Encarnacion MM, Warner GM, Gray CE, Nath KA, Grande JP. TGF-beta1 stimulates monocyte chemoattractant protein-1 expression in mesangial cells through a phosphodiesterase isoenzyme 4-dependent process. Am J Physiol Cell Physiol. 2005 Oct; 289 (4):C959-70 Epub 2005 June 01 View PubMed Chade AR, Mushin OP, Zhu X, Rodriguez-Porcel M, Grande JP, Textor SC, Lerman A, Lerman LO. Pathways of renal fibrosis and modulation of matrix turnover in experimental hypercholesterolemia. Hypertension. 2005 Oct; 46 (4):772-9 Epub 2005 Sept 19 View PubMed Uchiyama E, Kitaoka HB, Luo ZP, Grande JP, Kura H, An KN. Pathomechanics of hallux valgus: Biomechanical and immunohistochemical study. Foot Ankle Intl. 2005 Sep; 26(9):732-8. View PubMed Pittock ST, Norby SM, Grande JP, Croatt AJ, Bren GD, Badley AD, Caplice NM, Griffin MD, Nath KA. MCP-1 is up-regulated in unstressed and stressed HO-1 knockout mice: Pathophysiologic correlates. Kidney Int. 2005 Aug; 68 (2):611-22 View PubMed Dingli D, Larson DR, Plevak MF, Grande JP, Kyle RA. Focal and segmental glomerulosclerosis and plasma cell proliferative disorders. Am J Kidney Dis. 2005 Aug; 46(2):278-82. View PubMed Tebben PJ, Kalli KR, Cliby WA, Hartmann LC, Grande JP, Singh RJ, Kumar R. Elevated fibroblast growth factor 23 in women with malignant ovarian tumors. Mayo Clin Proc. 2005 Jun; 80 (6):745-51 View PubMed Gami AS, Hayman SR, Grande JP, Garovic VD. Incidence and prognosis of acute heart failure in the thrombotic microangiopathies. Am J Med. 2005 May; 118 (5):544-7 View PubMed Cosio FG, Grande JP, Larson TS, Gloor JM, Velosa JA, Textor SC, Griffin MD, Stegall MD. Kidney allograft fibrosis and atrophy early after living donor transplantation. Am J Transplant. 2005 May; 5 (5):1130-6 View PubMed Nath KA, Grande JP, Croatt AJ, Frank E, Caplice NM, Hebbel RP, Katusic ZS. Transgenic sickle mice are markedly sensitive to renal ischemia-reperfusion injury. Am J Pathol. 2005 Apr; 166 (4):963-72 View PubMed Cheng J, Thompson MA, Walker HJ, Gray CE, Diaz Encarnacion MM, Warner GM, Grande JP. Differential regulation of mesangial cell mitogenesis by cAMP phosphodiesterase isozymes 3 and 4. Am J Physiol Renal Physiol. 2004 Nov; 287(5):F940-53. Epub 2004 Jul 27. View PubMed Ninova D, Covarrubias M, Rea DJ, Park WD, Grande JP, Stegall MD. Acute nephrotoxicity of tacrolimus and sirolimus in renal isografts: differential intragraft expression of transforming growth factor-beta1 and alpha-smooth muscle actin. Transplantation. 2004 Aug 15; 78 (3):338-44 View PubMed Cleary MP, Grande JP, Maihle NJ. Effect of high fat diet on body weight and mammary tumor latency in MMTV-TGF-alpha mice. Int J Obes. 2004 Aug; 28(8):956-62. View PubMed Donadio JV, Grande JP. The role of fish oil/omega-3 fatty acids in the treatment of IgA nephropathy. Semin Nephrol. 2004 May; 24 (3):225-43 View PubMed Chade AR, Rodriguez-Porcel M, Herrmann J, Zhu X, Zhu X, Grande JP, Napoli C, Lerman A, Lerman LO. Antioxidant intervention blunts renal injury in experimental renovascular disease. J Am Soc Nephrol. 2004 Apr; 15 (4):958-66 View PubMed Cleary MP, Juneja SC, Phillips FC, Hu X, Grande JP, Maihle NJ. Leptin receptor-deficient MMTV-TGF-alpha/Lept(db) Lepr(db) female mice do not develop oncogene-induced mammary tumors. Experimental Biology & Medicine. 2004 Feb; 229(2):182-93. View PubMed Diaz Encarnacion MM, Griffin MD, Slezak JM, Bergstralh EJ, Stegall MD, Velosa JA, Grande JP. Correlation of quantitative digital image analysis with the glomerular filtration rate in chronic allograft nephropathy. Am J Transplant. 2004 Feb; 4 (2):248-56 View PubMed Fidler ME, Gloor JM, Lager DJ, Larson TS, Griffin MD, Textor SC, Schwab TR, Prieto M, Nyberg SL, Ishitani MB, Grande JP, Kay PA, Stegall MD. Histologic findings of antibody-mediated rejection in ABO blood-group-incompatible living-donor kidney transplantation. Am J Transplant. 2004 Jan; 4 (1):101-7 View PubMed Cleary MP, Grande JP, Juneja SC, Maihle NJ. Diet-induced obesity and mammary tumor development in MMTV-neu female mice. Nutrition & Cancer-An International Journal. 2004; 50(2):174-80. View PubMed Park WD, Grande JP, Ninova D, Nath KA, Platt JL, Gloor JM, Stegall MD. Accommodation in ABO-incompatible kidney allografts, a novel mechanism of self-protection against antibody-mediated injury. Am J Transplant. 2003 Aug; 3 (8):952-60 View PubMed Chade AR, Rodriguez-Porcel M, Grande JP, Zhu XY, Sica V, Napoli C, Sawamura T, Textor SC, Lerman A, Lerman LO. Mechanisms of renal structural alterations in combined hypercholesterolemia and renal artery stenosis. Arterioscler Thromb Vasc Biol. 2003 Jul; 23(7):1295-301. View PubMed Nath KA, Kanakiriya SK, Grande JP, Croatt AJ, Katusic ZS. Increased venous proinflammatory gene expression and intimal hyperplasia in an aorto-caval fistula model in the rat. Am J Pathol. 2003 Jun; 162 (6):2079-90 View PubMed Yusufi AN, Cheng J, Thompson MA, Walker HJ, Gray CE, Warner GM, Grande JP. Differential effects of low-dose docosahexaenoic acid and eicosapentaenoic acid on the regulation of mitogenic signaling pathways in mesangial cells. J Lab Clin Med. 2003 May; 141(5):318-29. View PubMed Gloor JM, Lager DJ, Moore SB, Pineda AA, Fidler ME, Larson TS, Grande JP, Schwab TR, Griffin MD, Prieto M, Nyberg SL, Velosa JA, Textor SC, Platt JL, Stegall MD. ABO-incompatible kidney transplantation using both A2 and non-A2 living donors. Transplantation. 2003 Apr 15; 75 (7):971-7 View PubMed Nyberg SL, Yagi T, Matsushita T, Hardin J, Grande JP, Gibson LE, Platt JL. Membrane barrier of a porcine hepatocyte bioartificial liver. Liver Transpl. 2003 Mar; 9(3):298-305. View PubMed Cleary MP, Phillips FC, Getzin SC, Jacobson TL, Jacobson MK, Christensen TA, Juneja SC, Grande JP, Maihle NJ. Genetically obese MMTV-TGF-alpha/Lep(ob)Lep(ob) female mice do not develop mammary tumors. Breast Cancer Research & Treatment. 2003 Feb; 77(3):205-15. View PubMed Kumar R, Pittelkow MR, Salisbury JL, Grande JP, Im HJ, Feldmann KA, Schilling D. A novel vitamin D-regulated immediate-early gene, IEX-1, alters cellular growth and apoptosis. Recent Results Cancer Res. 2003; 164:123-34 View PubMed Cheng J, Grande JP. Transforming growth factor-beta signal transduction and progressive renal disease. Exp Biol Med (Maywood). 2002 Dec; 227 (11):943-56 View PubMed Donadio JV, Grande JP. IgA nephropathy. N Engl J Med. 2002 Sep 5; 347 (10):738-48 View PubMed Cleary MP, Jacobson MK, Phillips FC, Getzin SC, Grande JP, Maihle NJ. Weight-cycling decreases incidence and increases latency of mammary tumors to a greater extent than does chronic caloric restriction in mouse mammary tumor virus-transforming growth factor-alpha female mice. Cancer Epidemiol Biomarkers Prev. 2002 Sep; 11(9):836-43. View PubMed Chade AR, Rodriguez-Porcel M, Grande JP, Krier JD, Lerman A, Romero JC, Napoli C, Lerman LO. Distinct renal injury in early atherosclerosis and renovascular disease. Circulation. 2002 Aug 27; 106 (9):1165-71 View PubMed Donadio JV, Bergstralh EJ, Grande JP, Rademcher DM. Proteinuria patterns and their association with subsequent end-stage renal disease in IgA nephropathy. Nephrol Dial Transplant. 2002 Jul; 17 (7):1197-203 View PubMed Gloor JM, Cohen AJ, Lager DJ, Grande JP, Fidler ME, Velosa JA, Larson TS, Schwab TR, Griffin MD, Prieto M, Nyberg SL, Sterioff S, Kremers WK, Stegall MD. Subclinical rejection in tacrolimus-treated renal transplant recipients. Transplantation. 2002 Jun 27; 73 (12):1965-8 View PubMed Bentley MD, Rodriguez-Porcel M, Lerman A, Sarafov MH, Romero JC, Pelaez LI, Grande JP, Ritman EL, Lerman LO. Enhanced renal cortical vascularization in experimental hypercholesterolemia. Kidney Int. 2002 Mar; 61(3):1056-63. View PubMed Grande JP, Warner GM, Walker HJ, Yusufi ANK, Cheng JF, Gray CE, Kopp JB, Nath KA. TGF-beta 1 is an autocrine mediator of renal tubular epithelial cell growth and collagen IV production. Experimental Biology & Medicine. 2002 Mar; 227(3):171-81. Grande JP, Warner GM, Walker HJ, Yusufi AN, Cheng J, Gray CE, Kopp JB, Nath KA. TGF-beta1 is an autocrine mediator of renal tubular epithelial cell growth and collagen IV production. Exp Biol Med (Maywood). 2002 Mar; 227 (3):171-81 View PubMed Thompson DL, Sabbagh Y, Tenenhouse HS, Roche PC, Drezner MK, Salisbury JL, Grande JP, Poeschla EM, Kumar R. Ontogeny of Phex/PHEX protein expression in mouse embryo and subcellular localization in osteoblasts. J Bone Miner Res. 2002 Feb; 17: (2)311-20. View PubMed Yusufi ANK, Cheng JF, Thompson MA, Burnett JC, Grande JP. Differential mechanisms of Ca2+ release from vascular smooth muscle cell microsomes. Experimental Biology & Medicine. 2002 Jan; 227(1):36-44. Pape-Ansorge KA, Grande JP, Christensen TA, Maihle NJ, Cleary MP. Effect of moderate caloric restriction and/or weight cycling on mammary tumor incidence and latency in MMTV-Neu female mice. Nutrition and Cancer-An International Journal. 2002; 44(2):161-8. View PubMed Yusufi AN, Cheng J, Thompson MA, Burnett JC, Grande JP. Differential mechanisms of Ca(2+) release from vascular smooth muscle cell microsomes. Exp Biol Med (Maywood). 2002 Jan; 227 (1):36-44 View PubMed Grande JP, Donadio JV. Role of dietary fish oil supplementation in IgA nephropathy. Mechanistic implications. Minerva Urol Nefrol. 2001 Dec; 53: (4)201-9. View PubMed Leung N, Croatt AJ, Haggard JJ, Grande JP, Nath KA. Acute cholestatic liver disease protects against glycerol-induced acute renal failure in the rat. Kidney Int. 2001 Sep; 60 (3):1047-57 View PubMed Hart CY, Meyer DM, Tazelaar HD, Grande JP, Burnett JC Jr, Housmans PR, Redfield MM. Load versus humoral activation in the genesis of early hypertensive heart disease. Circulation. 2001 Jul 10; 104 (2):215-20 View PubMed Yusufi AN, Cheng J, Thompson MA, Dousa TP, Warner GM, Walker HJ, Grande JP. cADP-ribose/ryanodine channel/Ca2+-release signal transduction pathway in mesangial cells. Am J Physiol Renal Physiol. 2001 Jul; 281 (1):F91-F102 View PubMed Feldmann KA, Pittelkow MR, Roche PC, Kumar R, Grande JP. Expression of an immediate early gene, IEX-1, in human tissues. Histochem Cell Biol. 2001 Jun; 115 (6):489-97 View PubMed Donadio JV Jr, Larson TS, Bergstralh EJ, Grande JP. A randomized trial of high-dose compared with low-dose omega-3 fatty acids in severe IgA nephropathy. J Am Soc Nephrol. 2001 Apr; 12 (4):791-799 View PubMed Nath KA, Grande JP, Haggard JJ, Croatt AJ, Katusic ZS, Solovey A, Hebbel RP. Oxidative stress and induction of heme oxygenase-1 in the kidney in sickle cell disease. Am J Pathol. 2001 Mar; 158 (3):893-903 View PubMed Yusufi AN, Cheng J, Thompson MA, Chini EN, Grande JP. Nicotinic acid-adenine dinucleotide phosphate (NAADP) elicits specific microsomal Ca2+ release from mammalian cells. Biochem J. 2001 Feb 1; 353 (Pt 3):531-6 View PubMed Dean PG, Cohen AJ, Dalla Valle H, Grande JP, Diamond LE, Byrne GW, Logan JS, McGregor CG, Stegall MD. The effect of anti-alphaGal antibody removal with immunoabsorption and splenectomy on CD46 transgenic kidney xenograft survival. Transplant Proc. 2001 Feb-Mar; 33 (1-2):721-2 View PubMed Cheng J, Yusufi ANK, Thompson MA, Chini EN, Grande JP. Nicotinic acid adenine dinucleotide phosphate: a new Ca2+ releasing agent in kidney. J Am Soc Nephrol. 2001 Jan; 12 (1):54-60 View PubMed Nath KA, Vercellotti GM, Grande JP, Miyoshi H, Paya CV, Manivel JC, Haggard JJ, Croatt AJ, Payne WD, Alam J. Heme protein-induced chronic renal inflammation: suppressive effect of induced heme oxygenase-1. Kidney Int. 2001 Jan; 59 (1):106-17 View PubMed Nath KA, Croatt AJ, Haggard JJ, Grande JP. Renal response to repetitive exposure to heme proteins: chronic injury induced by an acute insult. Kidney Int. 2000 Jun; 57(6):2423-33. View PubMed Nath KA, Haggard JJ, Croatt AJ, Grande JP, Poss KD, Alam J. The indispensability of heme oxygenase-1 in protecting against acute heme protein-induced toxicity in vivo. Am J Pathol. 2000 May; 156 (5):1527-35 View PubMed Grande JP, Walker HJ, Holub BJ, Warner GM, Keller DM, Haugen JD, Donadio JV Jr, Dousa TP. Suppressive effects of fish oil on mesangial cell proliferation in vitro and in vivo. Kidney Int. 2000 Mar; 57 (3):1027-40 View PubMed Stegall MD, Larson TS, Kudva YC, Grande JP, Nyberg SL, Prieto M, Velosa JA, Rizza RA. Pancreas transplantation for the prevention of diabetic nephropathy. Mayo Clin Proc. 2000 Jan; 75(1):49-56. View PubMed Donadio JV Jr, Grande JP, Bergstralh EJ, Dart RA, Larson TS, Spencer DC. The long-term outcome of patients with IgA nephropathy treated with fish oil in a controlled trial. Mayo Nephrology Collaborative Group. J Am Soc Nephrol. 1999 Aug; 10 (8):1772-7 View PubMed Lerman LO, Schwartz RS, Grande JP, Sheedy PF, Romero JC. Noninvasive evaluation of a novel swine model of renal artery stenosis. J Am Soc Nephrol. 1999 Jul; 10 (7):1455-65 View PubMed Racusen LC, Solez K, Colvin RB, Bonsib SM, Castro MC, Cavallo T, Croker BP, Demetris AJ, Drachenberg CB, Fogo AB, Furness P, Gaber LW, Gibson IW, Glotz D, Goldberg JC, Grande J, Halloran PF, Hansen HE, Hartley B, Hayry PJ, Hill CM, Hoffman EO, Hunsicker LG, Lindblad AS, Yamaguchi Y, et al. The Banff 97 working classification of renal allograft pathology. Kidney Int. 1999 Feb; 55(2):713-23. View PubMed Veenstra TD, Prufer K, Koenigsberger C, Brimijoin SW, Brimijoin SW, Grande JP, Kumar R. 1,25-Dihydroxyvitamin D3 receptors in the central nervous system of the rat embryo. Brain Res. 1998 Sep 7; 804 (2):193-205 View PubMed Imamura Y, Jin L, Grande JP, Li CY, Zheng TR, Erickson LA, Lloyd RV. Analysis of TGF-beta and TGF-beta-RII in thyroid neoplasms from the United States, Japan, and China. Endocr Pathol. 1998 Fal; 9(3):209-216. View PubMed Torres VE, Bengal RJ, Nickander KK, Grande JP, Low PA. Renal concentration of alpha-tocopherol: dependence on gender and lack of effect on polycystic kidney disease in Han:SPRD rats. Am J Kidney Dis. 1998 Apr; 31 (4):687-93 View PubMed Nath KA, Grande J, Croatt A, Haugen J, Kim Y, Rosenberg ME. Redox regulation of renal DNA synthesis, transforming growth factor-beta1 and collagen gene expression. Kidney Int. 1998 Feb; 53(2):367-81. View PubMed Griffin MD, Grande JP, Wiesner RH, Velosa JA. Prolonged anuria complicating primary sclerosing cholangitis: successful outcome following orthotopic liver transplantation. Am J Kidney Dis. 1998 Feb; 31 (2):360-3 View PubMed Nath KA, Grande JP, Croatt AJ, Likely S, Hebbel RP, Enright H. Intracellular targets in heme protein-induced renal injury. Kidney Int. 1998 Jan; 53 (1):100-11 View PubMed Grande JP, Balow JE. Renal biopsy in lupus nephritis. Lupus. 1998; 7: (9)611-7. View PubMed Grande JP, Donadio JV. N-3 Polyunsaturated fatty acids in the treatment of patients with IgA nephropathy. Progress in Inflammation Research: Medicinal Fatty Acids in Inflammation. 1998; 125-140. Grande JP. Mechanisms of progression of renal damage in lupus nephritis: pathogenesis of renal scarring. Lupus. 1998; 7: (9)604-10. View PubMed Griffin MD, O'Sullivan DA, Torres VE, Grande JP, Kanwar YS, Kumar R. Expression of polycystin in mouse metanephros and extra-metanephric tissues. Kidney Int. 1997 Nov; 52 (5):1196-205 View PubMed Grande JP, Melder DC, Zinsmeister AR. Modulation of collagen gene expression by cytokines: stimulatory effect of transforming growth factor-beta1, with divergent effects of epidermal growth factor and tumor necrosis factor-alpha on collagen type I and collagen type IV. J Lab Clin Med. 1997 Nov; 130 (5):476-86 View PubMed Matousovic K, Tsuboi Y, Walker H, Grande JP, Dousa TP. Inhibitors of cyclic nucleotide phosphodiesterase isozymes block renal tubular cell proliferation induced by folic acid. J Lab Clin Med. 1997 Nov; 130 (5):487-95 View PubMed Chini EN, Chini CC, Bolliger C, Jougasaki M, Grande JP, Burnett JC Jr, Dousa TP. Cytoprotective effects of adrenomedullin in glomerular cell injury: central role of cAMP signaling pathway. Kidney Int. 1997 Oct; 52 (4):917-25 View PubMed Donadio JV Jr, Grande JP. Immunoglobulin A nephropathy: a clinical perspective. J Am Soc Nephrol. 1997 Aug; 8 (8):1324-32 View PubMed Wyatt RJ, Emancipator SN, Kon V, Waldo FB, Donadio J, Grande JP, Andreoli SP, Glassock RJ. IgA nephropathy databank: development of a system for management of renal biopsy acquired data. Am J Kidney Dis. 1997 Jun; 29(6):817-28. View PubMed Chini EN, Klener P Jr, Beers KW, Chini CC, Grande JP, Dousa TP. Cyclic ADP-ribose metabolism in rat kidney: high capacity for synthesis in glomeruli. Kidney Int. 1997 May; 51 (5):1500-6 View PubMed Chini CC, Grande JP, Chini EN, Dousa TP. Compartmentalization of cAMP signaling in mesangial cells by phosphodiesterase isozymes PDE3 and PDE4. Regulation of superoxidation and mitogenesis. J Biol Chem. 1997 Apr 11; 272(15):9854-9. View PubMed Griffin MD, Torres VE, Grande JP, Kumar R. Vascular expression of polycystin. J Am Soc Nephrol. 1997 Apr; 8 (4):616-26 View PubMed Radford MG Jr, Donadio JV Jr, Bergstralh EJ, Grande JP. Predicting renal outcome in IgA nephropathy. J Am Soc Nephrol. 1997 Feb; 8 (2):199-207 View PubMed Grande JP. Role of transforming growth factor-beta in tissue injury and repair. Proc Soc Exp Biol Med. 1997 Jan; 214 (1):27-40 View PubMed Grande JP, Melder DC, Kluge DL, Wieben ED. Structure of the rat collagen IV promoter. Biochim Biophys Acta. 1996 Nov 11; 1309 (1-2):85-8 View PubMed Vrana JA, Stang MT, Grande JP, Getz MJ. Expression of tissue factor in tumor stroma correlates with progression to invasive human breast cancer: paracrine regulation by carcinoma cell-derived members of the transforming growth factor beta family. Cancer Res. 1996 Nov 1; 56(21):5063-70. Radford MG Jr, Holley KE, Grande JP, Larson TS, Wagoner RD, Donadio JV, McCarthy JT. Reversible membranous nephropathy associated with the use of nonsteroidal anti-inflammatory drugs. JAMA. 1996 Aug 14; 276 (6):466-9 View PubMed Tsuboi Y, Shankland SJ, Grande JP, Walker HJ, Johnson RJ, Dousa TP. Suppression of mesangial proliferative glomerulonephritis development in rats by inhibitors of cAMP phosphodiesterase isozymes types III and IV. J Clin Invest. 1996 Jul 15; 98 (2):262-70 View PubMed Qian X, Jin L, Grande JP, Lloyd RV. Transforming growth factor-beta and p27 expression in pituitary cells. Endocrinology. 1996 Jul; 137(7):3051-60. View PubMed Griffin MD, Torres VE, Grande JP, Kumar R. Immunolocalization of polycystin in human tissues and cultured cells. Proc Assoc Am Physicians. 1996 May; 108: (3)185-97. View PubMed Johnson JA, Grande JP, Windebank AJ, Kumar R. 1,25-Dihydroxyvitamin D(3) receptors in developing dorsal root ganglia of fetal rats. Brain Res Dev Brain Res. 1996 Mar 29; 92 (1):120-4 View PubMed Johnson JA, Grande JP, Roche PC, Kumar R. Immunohistochemical detection and distribution of the 1,25-dihydroxyvitamin D3 receptor in rat reproductive tissues. Histochem Cell Biol. 1996 Jan; 105 (1):7-15 View PubMed Johnson JA, Grande JP, Roche PC, Kumar R. Ontogeny of the 1,25-dihydroxyvitamin D3 receptor in fetal rat bone. J Bone Miner Res. 1996 Jan; 11: (1)56-61. View PubMed Chini EN, Choi E, Grande JP, Burnett JC, Dousa TP. Adrenomedullin suppresses mitogenesis in rat mesangial cells via cAMP pathway. Biochem Biophys Res Commun. 1995 Oct 24; 215(3):868-73. View PubMed Johnson JA, Grande JP, Roche PC, Sweeney WE Jr, Avner ED, Kumar R. 1 alpha, 25-dihydroxyvitamin D3 receptor ontogenesis in fetal renal development. Am J Physiol. 1995 Sep; 269 (3 Pt 2):F419-28 View PubMed Matousovic K, Grande JP, Chini CC, Chini EN, Dousa TP. Inhibitors of cyclic nucleotide phosphodiesterase isozymes type-III and type-IV suppress mitogenesis of rat mesangial cells. J Clin Invest. 1995 Jul; 96 (1):401-10 View PubMed Johnson JA, Grande JP, Roche PC, Campbell RJ, Kumar R. Immuno-localization of the calcitriol receptor, calbindin-D28k and the plasma membrane calcium pump in the human eye. Curr Eye Res. 1995 Feb; 14 (2):101-8 View PubMed Johnson JA, Grande JP, Roche PC, Campbell RJ, Kumar R. Immunolocalization of calcitriol receptor, plasma membrane calcium pump and calbindin-D28k in the cornea and ciliary body of the rat eye. Ophthalmic Res. 1995; 27 (1):42-7 View PubMed Wu A, Lewis DA, Michener SR, Tazelaar HD, Grande JP, McGregor CGA, Miller VM. Modulation of renal endothelin receptors during rejection of lung allografts. Endothelium. 1995; 3(4):331-42. Radford MG Jr, Donadio JV Jr, Holley KE, Bjornsson J, Grande JP. Renal biopsy in clinical practice. Mayo Clin Proc. 1994 Oct; 69 (10):983-4 View PubMed Johnson JA, Grande JP, Roche PC, Kumar R. Immunohistochemical localization of the 1,25(OH)2D3 receptor and calbindin D28k in human and rat pancreas. Am J Physiol. 1994 Sep; 267 (3 Pt 1):E356-60 View PubMed Grande JP, Jones ML, Swenson CL, Killen PD, Warren JS. Lipopolysaccharide induces monocyte chemoattractant protein production by rat mesangial cells. Journal of Laboratory & Clinical Medicine. 1994 Jul; 124(1):112-7. View PubMed Kumar R, Schaefer J, Grande JP, Roche PC. Immunolocalization of calcitriol receptor, 24-hydroxylase cytochrome P-450, and calbindin D28k in human kidney. Am J Physiol. 1994 Mar; 266 (3 Pt 2):F477-85 View PubMed Grande J, Melder D, Zinsmeister A, Killen P. Transforming growth factor-beta 1 induces collagen IV gene expression in NIH-3T3 cells. Lab Invest. 1993 Oct; 69(4):387-95. View PubMed Witzig TE, Gonchoroff NJ, Therneau T, Gilbertson DT, Wold LE, Grant C, Grande J, Katzmann JA, Ahmann DL, Ingle JN. DNA content flow cytometry as a prognostic factor for node-positive breast cancer. The role of multiparameter ploidy analysis and specimen sonication. Cancer. 1991 Oct 15; 68 (8):1781-8 View PubMed Killen PD, DeMeester CA, Long RA, O'Brien E, Grande JP. Regulation of collagen IV biosynthesis. the XIth International Congress of Nephrology M Hatano Ed, 1156-1162 () 1991; Nephrology:Proceedings of. Grande JP, Pellikka PA, Edwards WD, Puga FJ. Cardiogastric fistula occurring 9 years after resection of left ventricular aneurysm. Int J Cardiol. 1990 Jun; 27 (3):327-31 View PubMed Grande JP, Ackermann DM, Edwards WD. Aortoenteric fistulas. A study of 28 autopsied cases spanning 25 years. Archives of Pathology & Laboratory Medicine. 1989 Nov; 113(11):1271-5. View PubMed Grande JP, Glagov S, Bates SR, Horwitz AL, Mathews MB. Effect of normolipemic and hyperlipemic serum on biosynthetic response to cyclic stretching of aortic smooth muscle cells. Arteriosclerosis. 1989 Jul-Aug; 9(4):446-52. View PubMed Glagov S, Grande JP, Xu CP, Giddens DP, Zarins CK. Limited effects of hyperlipidemia on the arterial smooth muscle response to mechanical stress. J Cardiovasc Pharmacol 14 Suppl Review. 1989; 6:S90-7. Hyma BA, Moore SB, Grande JP, Talmo JJ, Reisner RK, Rakela J, Krom RA. Delayed immune hemolysis in a patient receiving cyclosporine after orthotopic liver transplantation. Transfusion. 1988 May-Jun; 28 (3):276-9 View PubMed Nam MH, Grande JP, Li CY, Kottke BA, Pineda AA, Weiland LH. Familial hypercholesterolemia with unusual foamy histiocytes. Report of a case with myelophthisic anemia and xanthoma of the maxillary sinus. Am J Clin Pathol. 1988 Apr; 89 (4):556-61 View PubMed Grande J, Davis HR, Bates S, Mathews MB, Glagov S. Effect of an elastin growth substrate on cholesteryl ester synthesis and foam cell formation by cultured aortic smooth muscle cells. Atherosclerosis. 1987 Nov; 68(1-2):87-93. View PubMed Scott NA, Grande JP, Weiland LH, Pemberton JH, Beart RW Jr, Lieber MM. Flow cytometric DNA patterns from colorectal cancers--how reproducible are they? Mayo Clin Proc. 1987 May; 62(5):331-7. View PubMed PST-20513136 الصفحة الرئيسية المنشورات